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Ylpm1 Gene Detail
Summary
  • Symbol
    Ylpm1
  • Name
    YLP motif containing 1
  • Synonyms
    A930013E17Rik, ZAP, Zap3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926195
    NCBI Gene: 56531
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:85043095-85117289 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 39.50 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    237 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926195
 protein coding gene Chr12:85042977-85134842 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019950
 protein coding gene Chr12:85751032-85825869 (+)
A/J MGP_AJ_G0019907
 protein coding gene Chr12:82498756-82573860 (+)
AKR/J MGP_AKRJ_G0019883
 protein coding gene Chr12:84724293-84798453 (+)
BALB/cJ MGP_BALBcJ_G0019887
 protein coding gene Chr12:82832896-82906615 (+)
C3H/HeJ MGP_C3HHeJ_G0019693
 protein coding gene Chr12:85202912-85277841 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020338
 protein coding gene Chr12:88216346-88297151 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017956
 protein coding gene Chr12:79381840-79458373 (+)
CAST/EiJ MGP_CASTEiJ_G0019242
 protein coding gene Chr12:80168040-80246373 (+)
CBA/J MGP_CBAJ_G0019664
 protein coding gene Chr12:91620406-91695592 (+)
DBA/2J MGP_DBA2J_G0019779
 protein coding gene Chr12:82015174-82088986 (+)
FVB/NJ MGP_FVBNJ_G0019765
 protein coding gene Chr12:80975823-81049901 (+)
LP/J MGP_LPJ_G0019851
 protein coding gene Chr12:85620989-85701217 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019804
 protein coding gene Chr12:94492328-94570132 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020372
 protein coding gene Chr12:84331247-84405022 (+)
PWK/PhJ MGP_PWKPhJ_G0019006
 protein coding gene Chr12:76505058-76580042 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018801
 protein coding gene Chr12:78805096-78892034 (+)
WSB/EiJ MGP_WSBEiJ_G0019294
 protein coding gene Chr12:85051109-85128664 (+)



Homology
more
  • Human Ortholog
    YLPM1, YLP motif containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    YLPM1, YLP motif containing 1
  • Synonyms
    C14orf170, PPP1R169, ZAP113, ZAP3
  • Links
    NCBI Gene ID: 56252
    neXtProt AC: NX_P49750
    UniProt: P49750

  • Chr Location
    14q24.3; chr14:74763316-74859435 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 1 allele in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    772
  • Tissues
    54
  • cDNA Data
    111
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021244 Ensembl Gene Model | MGI Sequence Detail 74195 C57BL/6J ±  kb
    transcript ENSMUST00000021670 Ensembl | MGI Sequence Detail 7003 Not Applicable  
    polypeptide ENSMUSP00000021670 Ensembl | MGI Sequence Detail 2139 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 112
      cDNA 111
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144901, MGI:2444150
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 12
    • Earliest
      J:64959 Misawa K, et al., A method to identify cDNAs based on localization of green fluorescent protein fusion products. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3062-6
    • Latest
      J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory