About   Help   FAQ
Igsf3 Gene Detail
Summary
  • Symbol
    Igsf3
  • Name
    immunoglobulin superfamily, member 3
  • Synonyms
    1700016K10Rik, 2810035F16Rik, 4833439O17Rik, mKIAA0466
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926158
    NCBI Gene: 78908
  • Alliance
  • Transcription Start Sites
    7 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr3:101284399-101370375 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 44.30 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    685 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926158
protein coding gene Chr3:101284306-101370375 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027675
protein coding gene Chr3:102549956-102639360 (+)
A/J MGP_AJ_G0027634
protein coding gene Chr3:99304797-99391952 (+)
AKR/J MGP_AKRJ_G0027600
protein coding gene Chr3:101756414-101845919 (+)
BALB/cJ MGP_BALBcJ_G0027647
protein coding gene Chr3:99057421-99144279 (+)
C3H/HeJ MGP_C3HHeJ_G0027376
protein coding gene Chr3:102046880-102133740 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028090
protein coding gene Chr3:106319423-106411033 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025431
protein coding gene Chr3:95499602-95586844 (+)
CAST/EiJ MGP_CASTEiJ_G0026832
protein coding gene Chr3:101144606-101236244 (+)
CBA/J MGP_CBAJ_G0027351
protein coding gene Chr3:109972105-110066764 (+)
DBA/2J MGP_DBA2J_G0027494
protein coding gene Chr3:98545083-98631974 (+)
FVB/NJ MGP_FVBNJ_G0027462
protein coding gene Chr3:96484021-96571145 (+)
LP/J MGP_LPJ_G0027601
protein coding gene Chr3:103903677-103991166 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027492
protein coding gene Chr3:116165315-116256013 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028145
protein coding gene Chr3:101240575-101329265 (+)
PWK/PhJ MGP_PWKPhJ_G0026559
protein coding gene Chr3:98301833-98389476 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026381
protein coding gene Chr3:99320327-99412549 (+)
WSB/EiJ MGP_WSBEiJ_G0026912
protein coding gene Chr3:101803097-101893220 (+)



Homology
more
  • Human Ortholog
    IGSF3, immunoglobulin superfamily member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGSF3, immunoglobulin superfamily member 3
  • Synonyms
    EWI-3, LCDD, V8
  • Links
    NCBI Gene ID: 3321
    neXtProt AC: NX_O75054
    UniProt: O75054

  • Chr Location
    1p13.1; chr1:116574398-116667755 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human IGSF3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042035 Ensembl Gene Model | MGI Sequence Detail 85977 C57BL/6J ±  kb
transcript ENSMUST00000195164 Ensembl | MGI Sequence Detail 3876 Not Applicable  
polypeptide ENSMUSP00000141823 Ensembl | MGI Sequence Detail 1214 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919956, MGI:1922800
References
more
  • Summaries
    All 43
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:341537 Tanjore Ramanathan J, et al., Immunoglobulin superfamily member 3 is required for the vagal neural crest cell migration and enteric neuronal network organization. Sci Rep. 2023 Oct 11;13(1):17162

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory