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Mrps5 Gene Detail
Summary
  • Symbol
    Mrps5
  • Name
    mitochondrial ribosomal protein S5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924971
    NCBI Gene: 77721
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:127429346-127445906 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 62.05 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    235 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924971
 protein coding gene Chr2:127429142-127448749 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026464
 protein coding gene Chr2:130879875-130899482 (+)
A/J MGP_AJ_G0026428
 protein coding gene Chr2:125577764-125597396 (+)
AKR/J MGP_AKRJ_G0026403
 protein coding gene Chr2:129158188-129177795 (+)
BALB/cJ MGP_BALBcJ_G0026440
 protein coding gene Chr2:125843753-125863877 (+)
C3H/HeJ MGP_C3HHeJ_G0026183
 protein coding gene Chr2:129675193-129694862 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026885
 protein coding gene Chr2:134984420-135004118 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024262
 protein coding gene Chr2:120423139-120442559 (+)
CAST/EiJ MGP_CASTEiJ_G0025644
 protein coding gene Chr2:129876082-129895742 (+)
CBA/J MGP_CBAJ_G0026163
 protein coding gene Chr2:139981619-140001295 (+)
DBA/2J MGP_DBA2J_G0026297
 protein coding gene Chr2:124983282-125003539 (+)
FVB/NJ MGP_FVBNJ_G0026261
 protein coding gene Chr2:123636873-123657064 (+)
LP/J MGP_LPJ_G0026402
 protein coding gene Chr2:131124752-131144359 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026281
 protein coding gene Chr2:143994290-144016059 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026940
 protein coding gene Chr2:129182537-129202144 (+)
PWK/PhJ MGP_PWKPhJ_G0025380
 protein coding gene Chr2:124531983-124551707 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025182
 protein coding gene Chr2:128266219-128287286 (+)
WSB/EiJ MGP_WSBEiJ_G0025718
 protein coding gene Chr2:130087962-130107575 (+)



Homology
more
  • Human Ortholog
    MRPS5, mitochondrial ribosomal protein S5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPS5, mitochondrial ribosomal protein S5
  • Synonyms
    MRP-S5, S5mt, uS5m
  • Links
    NCBI Gene ID: 64969
    neXtProt AC: NX_P82675
    UniProt: P82675

  • Chr Location
    2q11.1; chr2:95085369-95122006 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    12
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    13
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 77721 NCBI Gene Model | MGI Sequence Detail 16561 C57BL/6J ±  kb
transcript NM_029963 RefSeq | MGI Sequence Detail 1448 Not Specified  
polypeptide Q99N87 UniProt | EBI | MGI Sequence Detail 432 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010643 small ribosomal subunit protein uS5m
    (term hierarchy)
  • PDB
    7PNT, 7PNU, 7PNV, 7PNW
  • InterPro Domains
    IPR020568 Ribosomal protein uS5 domain 2-type superfamily
    IPR000851 Small ribosomal subunit protein uS5
    IPR005324 Small ribosomal subunit protein uS5, C-terminal
    IPR014721 Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
    IPR048584 Small ribosomal subunit protein uS5m, N-terminal domain
    IPR013810 Small ribosomal subunit protein uS5, N-terminal
    IPR018192 Small ribosomal subunit protein uS5, N-terminal, conserved site
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:2139078
References
more
  • Summaries
    All 50
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 17
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:336424 Gao F, et al., A defect in mitochondrial protein translation influences mitonuclear communication in the heart. Nat Commun. 2023 Mar 22;14(1):1595
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory