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Mzt1 Gene Detail
Summary
  • Symbol
    Mzt1
  • Name
    mitotic spindle organizing protein 1
  • Synonyms
    2410129H14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924039
    NCBI Gene: 76789
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:99271980-99283570 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 49.22 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    167 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924039
protein coding gene Chr14:99271980-99283898 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021614
protein coding gene Chr14:95303901-95314985 (-)
A/J MGP_AJ_G0021572
protein coding gene Chr14:92267070-92279102 (-)
AKR/J MGP_AKRJ_G0021548
protein coding gene Chr14:94983032-94996271 (-)
BALB/cJ MGP_BALBcJ_G0021578
protein coding gene Chr14:92600612-92612266 (-)
C3H/HeJ MGP_C3HHeJ_G0021356
protein coding gene Chr14:94864471-94879926 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022018
protein coding gene Chr14:99192362-99206651 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019558
protein coding gene Chr14:89317000-89329070 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0021324
protein coding gene Chr14:102871635-102886197 (-)
DBA/2J MGP_DBA2J_G0021448
protein coding gene Chr14:91764442-91776353 (-)
FVB/NJ MGP_FVBNJ_G0021425
protein coding gene Chr14:90802813-90814187 (-)
LP/J MGP_LPJ_G0021516
protein coding gene Chr14:96110900-96122902 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021452
protein coding gene Chr14:105589117-105603240 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022041
protein coding gene Chr14:94477588-94488973 (-)
PWK/PhJ MGP_PWKPhJ_G0020616
protein coding gene Chr14:88741121-88753666 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020454
protein coding gene Chr14:90470167-90479820 (-)
WSB/EiJ MGP_WSBEiJ_G0020926
protein coding gene Chr14:95095610-95107757 (-)



Homology
more
  • Human Ortholog
    MZT1, mitotic spindle organizing protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MZT1, mitotic spindle organizing protein 1
  • Synonyms
    C13orf37, MOZART1
  • Links
    NCBI Gene ID: 440145
    neXtProt AC: NX_Q08AG7
    UniProt: Q08AG7

  • Chr Location
    13q21.33; chr13:72708367-72727629 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033186 Ensembl Gene Model | MGI Sequence Detail 11591 C57BL/6J ±  kb
transcript ENSMUST00000042662 Ensembl | MGI Sequence Detail 2240 Not Applicable  
polypeptide ENSMUSP00000037557 Ensembl | MGI Sequence Detail 78 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 79
    cDNA 78
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2147198
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:342865 Wan Y, et al., LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance. Nucleic Acids Res. 2023 Nov 27;51(21):11652-11667

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory