About   Help   FAQ
Clasp1 Gene Detail
Summary
  • Symbol
    Clasp1
  • Name
    CLIP associating protein 1
  • Synonyms
    1700030C23Rik, 5730583A19Rik, B130045P17Rik, CLASP1, CLASP1alpha, mCLASP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923957
    NCBI Gene: 76707
  • Alliance
    gene page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:118314976-118537192 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 52.14 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    943 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923957
 protein coding gene Chr1:118314976-118540408 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016391
 protein coding gene Chr1:121080834-121307024 (+)
A/J MGP_AJ_G0016374
 protein coding gene Chr1:116757276-116978442 (+)
AKR/J MGP_AKRJ_G0016339
 protein coding gene Chr1:120208775-120434408 (+)
BALB/cJ MGP_BALBcJ_G0016334
 protein coding gene Chr1:117017199-117237129 (+)
C3H/HeJ MGP_C3HHeJ_G0016160
 protein coding gene Chr1:120379840-120605351 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016795
 protein coding gene Chr1:125700962-125959988 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014508
 protein coding gene Chr1:110439186-110652424 (+)
CAST/EiJ MGP_CASTEiJ_G0015741
 protein coding gene Chr1:119101638-119327784 (+)
CBA/J MGP_CBAJ_G0016133
 protein coding gene Chr1:130072610-130313771 (+)
DBA/2J MGP_DBA2J_G0016239
 protein coding gene Chr1:115770953-115992421 (+)
FVB/NJ MGP_FVBNJ_G0016238
 protein coding gene Chr1:114499989-114719974 (+)
LP/J MGP_LPJ_G0016310
 protein coding gene Chr1:122427600-122653234 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016263
 protein coding gene Chr1:135860266-136087618 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016831
 protein coding gene Chr1:119893526-120128025 (+)
PWK/PhJ MGP_PWKPhJ_G0015527
 protein coding gene Chr1:114742505-114963879 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015315
 protein coding gene Chr1:118776675-119004904 (+)
WSB/EiJ MGP_WSBEiJ_G0015803
 protein coding gene Chr1:119788355-120014882 (+)



Homology
more
  • Human Ortholog
    CLASP1, cytoplasmic linker associated protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLASP1, cytoplasmic linker associated protein 1
  • Synonyms
    MAST1
  • Links
    NCBI Gene ID: 23332
    neXtProt AC: NX_Q7Z460
    UniProt: Q7Z460

  • Chr Location
    2q14.2-q14.3; chr2:121337776-121649476 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    65
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    3
  • cDNA Data
    213
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      216
    • RefSeq
      100
    • UniProt
      20
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76707 NCBI Gene Model | MGI Sequence Detail 222217 C57BL/6J ±  kb
    transcript NM_001293300 RefSeq | MGI Sequence Detail 7951 C57BL/6  
    polypeptide Q80TV8 UniProt | EBI | MGI Sequence Detail 1535 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 216
      cDNA 213
      Primer pair 3

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1917924, MGI:2443918
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 5
      Gene Ontology 10
      Phenotypes 14
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:333796 Ruiz-Reig N, et al., KIF2A deficiency causes early-onset neurodegeneration. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2209714119
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory