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Spatc1l Gene Detail
Summary
  • Symbol
    Spatc1l
  • Name
    spermatogenesis and centriole associated 1 like
  • Synonyms
    1700022B01Rik, 1700027D21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923823
    NCBI Gene: 76573
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:76398106-76406035 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923823
 protein coding gene Chr10:76394180-76406035 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017386
 protein coding gene Chr10:76814656-76822337 (+)
A/J MGP_AJ_G0017363
 protein coding gene Chr10:74156684-74164365 (+)
AKR/J MGP_AKRJ_G0017324
 protein coding gene Chr10:76155348-76163029 (+)
BALB/cJ MGP_BALBcJ_G0017323
 protein coding gene Chr10:74358984-74367455 (+)
C3H/HeJ MGP_C3HHeJ_G0017147
 protein coding gene Chr10:76233182-76241725 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017781
 protein coding gene Chr10:79516531-79524499 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015471
 protein coding gene Chr10:70602590-70608771 (+)
CAST/EiJ MGP_CASTEiJ_G0016717
 protein coding gene Chr10:76551523-76560757 (+)
CBA/J MGP_CBAJ_G0017119
 protein coding gene Chr10:82632283-82639964 (+)
DBA/2J MGP_DBA2J_G0017224
 protein coding gene Chr10:73458019-73465918 (+)
FVB/NJ MGP_FVBNJ_G0017216
 protein coding gene Chr10:72616415-72624096 (+)
LP/J MGP_LPJ_G0017297
 protein coding gene Chr10:77295887-77303582 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017245
 protein coding gene Chr10:84684306-84693089 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017820
 protein coding gene Chr10:76216645-76224574 (+)
PWK/PhJ MGP_PWKPhJ_G0016501
 protein coding gene Chr10:73304688-73312463 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016284
 protein coding gene Chr10:75441269-75449231 (+)
WSB/EiJ MGP_WSBEiJ_G0016780
 protein coding gene Chr10:76190806-76198486 (+)



Homology
more
  • Human Ortholog
    SPATC1L, spermatogenesis and centriole associated 1 like
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATC1L, spermatogenesis and centriole associated 1 like
  • Synonyms
    C21orf56
  • Links
    NCBI Gene ID: 84221
    neXtProt AC: NX_Q9H0A9
    UniProt: Q9H0A9

  • Chr Location
    21q22.3; chr21:46161148-46184476 (-)  GRCh38
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 2 alleles in 2 genetic backgrounds
    34 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a null mutation are infertile with acephalic sperm and detached sperm tails. Male mice heterozygous for a null mutation display reduced fertility with similar sperm abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    864
  • Tissues
    63
  • cDNA Data
    13
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000009115 Ensembl Gene Model | MGI Sequence Detail 7930 C57BL/6J ±  kb
    transcript ENSMUST00000009259 Ensembl | MGI Sequence Detail 1332 Not Applicable  
    polypeptide ENSMUSP00000009259 Ensembl | MGI Sequence Detail 342 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      Genomic 1
      cDNA 13
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1916661, MGI:2652136
    References
    more
    • Summaries
      All 60
      Developmental Gene Expression 3
      Diseases 2
      Gene Ontology 3
      Phenotypes 34
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:341136 Muza PM, et al., Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture. iScience. 2023 Feb 17;26(2):106073
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory