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Tmem14a Gene Detail
Summary
  • Symbol
    Tmem14a
  • Name
    transmembrane protein 14A
  • Synonyms
    5730496E24Rik, PTD011
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922962
    NCBI Gene: 75712
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:21288799-21300391 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 6.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    144 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922962
 protein coding gene Chr1:21236609-21300391 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015876
 protein coding gene Chr1:18853320-18866274 (+)
A/J MGP_AJ_G0015857
 protein coding gene Chr1:18620710-18633529 (+)
AKR/J MGP_AKRJ_G0015816
 protein coding gene Chr1:18666792-18679567 (+)
BALB/cJ MGP_BALBcJ_G0015813
 protein coding gene Chr1:18327491-18339283 (+)
C3H/HeJ MGP_C3HHeJ_G0015647
 protein coding gene Chr1:18702904-18715975 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016267
 protein coding gene Chr1:19738660-19753234 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013988
 protein coding gene Chr1:16782097-16793962 (+)
CAST/EiJ MGP_CASTEiJ_G0015228
 protein coding gene Chr1:18810416-18824691 (+)
CBA/J MGP_CBAJ_G0015620
 protein coding gene Chr1:20193981-20211799 (+)
DBA/2J MGP_DBA2J_G0015719
 protein coding gene Chr1:18132125-18145081 (+)
FVB/NJ MGP_FVBNJ_G0015724
 protein coding gene Chr1:17889949-17904235 (+)
LP/J MGP_LPJ_G0015791
 protein coding gene Chr1:19110443-19122039 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015742
 protein coding gene Chr1:21124557-21138951 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016314
 protein coding gene Chr1:18653321-18666531 (+)
PWK/PhJ MGP_PWKPhJ_G0015012
 protein coding gene Chr1:17854761-17873104 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014793
 protein coding gene Chr1:18755518-18779738 (+)
WSB/EiJ MGP_WSBEiJ_G0015291
 protein coding gene Chr1:18589617-18603545 (+)



Homology
more
  • Human Ortholog
    TMEM14A, transmembrane protein 14A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM14A, transmembrane protein 14A
  • Synonyms
    C6orf73, PTD011
  • Links
    NCBI Gene ID: 28978
    neXtProt AC: NX_Q9Y6G1
    UniProt: Q9Y6G1

  • Chr Location
    6p12.2; chr6:52671113-52686588 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    31
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025933 Ensembl Gene Model | MGI Sequence Detail 11593 C57BL/6J ±  kb
transcript ENSMUST00000027064 Ensembl | MGI Sequence Detail 1261 Not Applicable  
polypeptide ENSMUSP00000027064 Ensembl | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138709
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory