About   Help   FAQ
Zbtb3 Gene Detail
Summary
  • Symbol
    Zbtb3
  • Name
    zinc finger and BTB domain containing 3
  • Synonyms
    4930563M09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922541
    NCBI Gene: 75291
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:8779919-8782210 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 5.65 cM, cytoband A
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922541
protein coding gene Chr19:8779853-8783035 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024810
protein coding gene Chr19:6083461-6085785 (+)
A/J MGP_AJ_G0024778
protein coding gene Chr19:5754672-5756996 (+)
AKR/J MGP_AKRJ_G0024753
protein coding gene Chr19:5847334-5849658 (+)
BALB/cJ MGP_BALBcJ_G0024778
protein coding gene Chr19:5859163-5861487 (+)
C3H/HeJ MGP_C3HHeJ_G0024544
protein coding gene Chr19:5926982-5929306 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025225
protein coding gene Chr19:6205578-6207902 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022654
protein coding gene Chr19:6003144-6005467 (+)
CAST/EiJ MGP_CASTEiJ_G0024017
protein coding gene Chr19:5576782-5579106 (+)
CBA/J MGP_CBAJ_G0024518
protein coding gene Chr19:6323577-6325901 (+)
DBA/2J MGP_DBA2J_G0024645
protein coding gene Chr19:5586453-5588777 (+)
FVB/NJ MGP_FVBNJ_G0024612
protein coding gene Chr19:5660426-5662750 (+)
LP/J MGP_LPJ_G0024732
protein coding gene Chr19:5972055-5974379 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024639
protein coding gene Chr19:6189509-6191833 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025274
protein coding gene Chr19:5889327-5891651 (+)
PWK/PhJ MGP_PWKPhJ_G0023762
protein coding gene Chr19:5255350-5257674 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023567
protein coding gene Chr19:5496621-5498950 (+)
WSB/EiJ MGP_WSBEiJ_G0024079
protein coding gene Chr19:5857926-5860250 (+)



Homology
more
  • Human Ortholog
    ZBTB3, zinc finger and BTB domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBTB3, zinc finger and BTB domain containing 3
  • Links
    NCBI Gene ID: 79842
    UniProt: Q9H5J0

  • Chr Location
    11q12.3; chr11:62748319-62754184 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071661 Ensembl Gene Model | MGI Sequence Detail 2292 C57BL/6J ±  kb
transcript ENSMUST00000172175 Ensembl | MGI Sequence Detail 2004 Not Applicable  
polypeptide ENSMUSP00000127746 Ensembl | MGI Sequence Detail 518 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:308922 Medeiros de Araujo JA, et al., ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex. Development. 2021 Aug 15;148(16):dev196642

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory