About   Help   FAQ
Dnal1 Gene Detail
Summary
  • Symbol
    Dnal1
  • Name
    dynein, axonemal, light chain 1
  • Synonyms
    1700010H15Rik, Dnal1, Dnalc1, E330027P08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921462
    NCBI Gene: 105000
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:84161057-84190291 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 39.05 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    191 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921462
 protein coding gene Chr12:84161057-84194272 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019928
 protein coding gene Chr12:84796924-84831070 (+)
A/J MGP_AJ_G0019885
 protein coding gene Chr12:81591776-81624901 (+)
AKR/J MGP_AKRJ_G0019861
 protein coding gene Chr12:83798077-83834328 (+)
BALB/cJ MGP_BALBcJ_G0019865
 protein coding gene Chr12:81922089-81956337 (+)
C3H/HeJ MGP_C3HHeJ_G0019671
 protein coding gene Chr12:84274725-84309639 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020316
 protein coding gene Chr12:87240571-87273431 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017934
 protein coding gene Chr12:78500634-78535645 (+)
CAST/EiJ MGP_CASTEiJ_G0019220
 protein coding gene Chr12:79208943-79245399 (+)
CBA/J MGP_CBAJ_G0019642
 protein coding gene Chr12:90605274-90640877 (+)
DBA/2J MGP_DBA2J_G0019757
 protein coding gene Chr12:81123209-81156747 (+)
FVB/NJ MGP_FVBNJ_G0019743
 protein coding gene Chr12:80078963-80112444 (+)
LP/J MGP_LPJ_G0019829
 protein coding gene Chr12:84678431-84716062 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019782
 protein coding gene Chr12:93542206-93575227 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020350
 protein coding gene Chr12:83401752-83435001 (+)
PWK/PhJ MGP_PWKPhJ_G0018984
 protein coding gene Chr12:75608144-75641754 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018779
 protein coding gene Chr12:77876990-77912495 (+)
WSB/EiJ MGP_WSBEiJ_G0019272
 protein coding gene Chr12:84066449-84103010 (+)



Homology
more
  • Human Ortholog
    DNAL1, dynein axonemal light chain 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAL1, dynein axonemal light chain 1
  • Synonyms
    C14orf168, CILD16, LC1
  • Links
    NCBI Gene ID: 83544
    neXtProt AC: NX_Q4LDG9
    UniProt: Q4LDG9

  • Chr Location
    14q24.3; chr14:73644875-73703732 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human DNAL1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    3
  • cDNA Data
    9
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 105000 NCBI Gene Model | MGI Sequence Detail 29235 C57BL/6J ±  kb
    transcript NM_001346528 RefSeq | MGI Sequence Detail 5893 C57BL/6  
    polypeptide Q05A62 UniProt | EBI | MGI Sequence Detail 190 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2145006
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:110961 Horvath J, et al., Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients. Am J Respir Cell Mol Biol. 2005 Jul;33(1):41-7
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory