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Fbrsl1 Gene Detail
Summary
  • Symbol
    Fbrsl1
  • Name
    fibrosin-like 1
  • Synonyms
    2410025L10Rik, Gm29766, LOC381668
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920907
    NCBI Gene: 381668
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:110509617-110596369 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 53.51 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    567 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920907
 protein coding gene Chr5:110509617-110596468 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029888
 protein coding gene Chr5:112813642-112902399 (-)
A/J MGP_AJ_G0029853
 protein coding gene Chr5:108445074-108532651 (-)
AKR/J MGP_AKRJ_G0029791
 protein coding gene Chr5:111901296-111988881 (-)
BALB/cJ MGP_BALBcJ_G0029864
 protein coding gene Chr5:109808481-109899911 (-)
C3H/HeJ MGP_C3HHeJ_G0029584
 protein coding gene Chr5:112319569-112407498 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030317
 protein coding gene Chr5:117260277-117354065 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027546
 protein coding gene Chr5:103270190-103360177 (-)
CAST/EiJ MGP_CASTEiJ_G0028992
 protein coding gene Chr5:111184850-111278042 (-)
CBA/J MGP_CBAJ_G0029551
 protein coding gene Chr5:121671263-121766673 (-)
DBA/2J MGP_DBA2J_G0029701
 protein coding gene Chr5:108508946-108598736 (-)
FVB/NJ MGP_FVBNJ_G0029658
 protein coding gene Chr5:107182873-107272965 (-)
LP/J MGP_LPJ_G0029789
 protein coding gene Chr5:113377527-113467879 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029689
 protein coding gene Chr5:126323363-126414787 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030358
 protein coding gene Chr5:111328419-111415950 (-)
PWK/PhJ MGP_PWKPhJ_G0028706
 protein coding gene Chr5:107096618-107185364 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028544
 protein coding gene Chr5:108789370-108877660 (-)
WSB/EiJ MGP_WSBEiJ_G0029068
 protein coding gene Chr5:111798767-111887700 (-)



Homology
more
  • Human Ortholog
    FBRSL1, fibrosin like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBRSL1, fibrosin like 1
  • Links
    NCBI Gene ID: 57666
    neXtProt AC: NX_Q9HCM7
    UniProt: Q9HCM7

  • Chr Location
    12q24.33; chr12:132489551-132585188 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    1
  • cDNA Data
    8
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 381668 NCBI Gene Model | MGI Sequence Detail 86753 C57BL/6J ±  kb
    transcript NM_001142642 RefSeq | MGI Sequence Detail 4737 C57BL/6  
    polypeptide NP_001136114 RefSeq | MGI Sequence Detail 1031 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      11 Sequences
    • InterPro Domains
      IPR023246 Autism susceptibility gene 2 protein
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2140908, MGI:2685895, MGI:5588925
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Phenotypes 16
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory