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Ppil6 Gene Detail
Summary
  • Symbol
    Ppil6
  • Name
    peptidylprolyl isomerase (cyclophilin)-like 6
  • Synonyms
    2900084F20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920325
    NCBI Gene: 73075
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:41366435-41390282 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 22.43 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920325
 protein coding gene Chr10:41366414-41390286 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017175
 protein coding gene Chr10:40132329-40156085 (+)
A/J MGP_AJ_G0017152
 protein coding gene Chr10:39014786-39038967 (+)
AKR/J MGP_AKRJ_G0017112
 protein coding gene Chr10:39600162-39628166 (+)
BALB/cJ MGP_BALBcJ_G0017114
 protein coding gene Chr10:39083746-39107550 (+)
C3H/HeJ MGP_C3HHeJ_G0016935
 protein coding gene Chr10:39915680-39947002 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017573
 protein coding gene Chr10:41355490-41383052 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015269
 protein coding gene Chr10:36952706-36977094 (+)
CAST/EiJ MGP_CASTEiJ_G0016514
 protein coding gene Chr10:40117124-40142666 (+)
CBA/J MGP_CBAJ_G0016909
 protein coding gene Chr10:43240523-43270666 (+)
DBA/2J MGP_DBA2J_G0017014
 protein coding gene Chr10:38518834-38543472 (+)
FVB/NJ MGP_FVBNJ_G0017009
 protein coding gene Chr10:38018393-38042735 (+)
LP/J MGP_LPJ_G0017091
 protein coding gene Chr10:40120362-40151674 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017039
 protein coding gene Chr10:44064256-44089091 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017610
 protein coding gene Chr10:39581318-39605840 (+)
PWK/PhJ MGP_PWKPhJ_G0016294
 protein coding gene Chr10:38395460-38420082 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016078
 protein coding gene Chr10:39397109-39420059 (+)
WSB/EiJ MGP_WSBEiJ_G0016577
 protein coding gene Chr10:39906880-39932116 (+)



Homology
more
  • Human Ortholog
    PPIL6, peptidylprolyl isomerase like 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPIL6, peptidylprolyl isomerase like 6
  • Synonyms
    bA425D10.6, dJ919F19.1, PPIase, RSPH12
  • Links
    NCBI Gene ID: 285755
    neXtProt AC: NX_Q8IXY8
    UniProt: Q8IXY8

  • Chr Location
    6q21; chr6:109390215-109441171 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Ppil6
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    18 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078451 Ensembl Gene Model | MGI Sequence Detail 23848 C57BL/6J ±  kb
transcript ENSMUST00000105507 Ensembl | MGI Sequence Detail 1068 Not Applicable  
polypeptide ENSMUSP00000101146 Ensembl | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013088 probable inactive peptidyl-prolyl cis-trans isomerase-like 6
    (term hierarchy)
  • EC
    5.2.1.8
  • InterPro Domains
    IPR029000 Cyclophilin-like domain superfamily
    IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
    IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory