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Eml2 Gene Detail
Summary
  • Symbol
    Eml2
  • Name
    echinoderm microtubule associated protein like 2
  • Synonyms
    1600029N02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919455
    NCBI Gene: 72205
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:18910346-18940407 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.46 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    247 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919455
protein coding gene Chr7:18910322-18940407 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031764
protein coding gene Chr7:17139220-17173341 (+)
A/J MGP_AJ_G0031740
protein coding gene Chr7:16818002-16848352 (+)
AKR/J MGP_AKRJ_G0031666
protein coding gene Chr7:17274971-17304809 (+)
BALB/cJ MGP_BALBcJ_G0031745
protein coding gene Chr7:17010633-17050196 (+)
C3H/HeJ MGP_C3HHeJ_G0031467
protein coding gene Chr7:17540663-17574233 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032211
protein coding gene Chr7:18025183-18055092 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029277
protein coding gene Chr7:18465214-18494772 (+)
CAST/EiJ MGP_CASTEiJ_G0030810
protein coding gene Chr7:13938230-13978092 (+)
CBA/J MGP_CBAJ_G0031429
protein coding gene Chr7:18680810-18722618 (+)
DBA/2J MGP_DBA2J_G0031584
protein coding gene Chr7:16752918-16785606 (+)
FVB/NJ MGP_FVBNJ_G0031536
protein coding gene Chr7:16617512-16649215 (+)
LP/J MGP_LPJ_G0031667
protein coding gene Chr7:17478877-17512393 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031572
protein coding gene Chr7:18536621-18569659 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032239
protein coding gene Chr7:16885739-16916005 (+)
PWK/PhJ MGP_PWKPhJ_G0030534
protein coding gene Chr7:13841964-13872708 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030361
protein coding gene Chr7:11581678-11622929 (+)
WSB/EiJ MGP_WSBEiJ_G0030910
protein coding gene Chr7:17093472-17129177 (+)



Homology
more
  • Human Ortholog
    EML2, EMAP like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EML2, EMAP like 2
  • Synonyms
    ELP70, EMAP2, EMAP-2
  • Links
    NCBI Gene ID: 24139
    neXtProt AC: NX_O95834
    UniProt: O95834

  • Chr Location
    19q13.32; chr19:45606994-45645629 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040811 Ensembl Gene Model | MGI Sequence Detail 30062 C57BL/6J ±  kb
    transcript ENSMUST00000117338 Ensembl | MGI Sequence Detail 2765 Not Applicable  
    polypeptide ENSMUSP00000112491 Ensembl | MGI Sequence Detail 841 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 34
      cDNA 31
      Primer pair 3

      Microarray probesets 3
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:300487 Chai G, et al., Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/19/2024
    MGI 6.23
    The Jackson Laboratory