About   Help   FAQ
Ints11 Gene Detail
Summary
  • Symbol
    Ints11
  • Name
    integrator complex subunit 11
  • Synonyms
    2410006F12Rik, Cpsf3l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919207
    NCBI Gene: 71957
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:155954006-155973561 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 87.66 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    307 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919207
 protein coding gene Chr4:155954003-155973561 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029236
 protein coding gene Chr4:160240006-160261890 (+)
A/J MGP_AJ_G0029201
 protein coding gene Chr4:153487882-153508318 (+)
AKR/J MGP_AKRJ_G0029149
 protein coding gene Chr4:157666651-157686329 (+)
BALB/cJ MGP_BALBcJ_G0029217
 protein coding gene Chr4:153961574-153981439 (+)
C3H/HeJ MGP_C3HHeJ_G0028938
 protein coding gene Chr4:158209282-158229043 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029666
 protein coding gene Chr4:165916948-165939423 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026910
 protein coding gene Chr4:145776364-145795322 (+)
CAST/EiJ MGP_CASTEiJ_G0028350
 protein coding gene Chr4:155680788-155699892 (+)
CBA/J MGP_CBAJ_G0028900
 protein coding gene Chr4:170931765-170956072 (+)
DBA/2J MGP_DBA2J_G0029049
 protein coding gene Chr4:153508729-153529511 (+)
FVB/NJ MGP_FVBNJ_G0029012
 protein coding gene Chr4:152758053-152780137 (+)
LP/J MGP_LPJ_G0029139
 protein coding gene Chr4:160167453-160191666 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029039
 protein coding gene Chr4:173745470-173765497 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029698
 protein coding gene Chr4:158292705-158318965 (+)
PWK/PhJ MGP_PWKPhJ_G0028071
 protein coding gene Chr4:149652255-149672464 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027905
 protein coding gene Chr4:152551900-152574785 (+)
WSB/EiJ MGP_WSBEiJ_G0028430
 protein coding gene Chr4:158466726-158489220 (+)



Homology
more
  • Human Ortholog
    INTS11, integrator complex subunit 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INTS11, integrator complex subunit 11
  • Synonyms
    CPSF3L, CPSF73L, INT11, NEDMLOB, PSF3L, RC68, RC-68
  • Links
    NCBI Gene ID: 54973
    neXtProt AC: NX_Q5TA45
    UniProt: Q5TA45

  • Chr Location
    1p36.33; chr1:1311585-1324687 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human INTS11 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    89
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71957 NCBI Gene Model | MGI Sequence Detail 19556 C57BL/6J ±  kb
transcript NM_028020 RefSeq | MGI Sequence Detail 2350 ZRU/MplStud  
polypeptide Q9CWS4 UniProt | EBI | MGI Sequence Detail 600 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 91
    Genomic 1
    cDNA 90

    Microarray probesets 2
Other
Accession IDs
less
MGI:2140491
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:229253 Spies N, et al., Constraint and divergence of global gene expression in the mammalian embryo. Elife. 2015;4:e05538
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory