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Tekt3 Gene Detail
Summary
  • Symbol
    Tekt3
  • Name
    tektin 3
  • Synonyms
    4933407G07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918312
    NCBI Gene: 71062
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:62952485-62985786 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 38.92 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918312
protein coding gene Chr11:62952480-62985790 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018467
protein coding gene Chr11:63154158-63191971 (+)
A/J MGP_AJ_G0018436
protein coding gene Chr11:60810946-60844801 (+)
AKR/J MGP_AKRJ_G0018405
protein coding gene Chr11:62686431-62723963 (+)
BALB/cJ MGP_BALBcJ_G0018407
protein coding gene Chr11:61085587-61119537 (+)
C3H/HeJ MGP_C3HHeJ_G0018220
protein coding gene Chr11:62658565-62694195 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018859
protein coding gene Chr11:65128788-65165262 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016503
protein coding gene Chr11:57881990-57918888 (+)
CAST/EiJ MGP_CASTEiJ_G0017776
protein coding gene Chr11:62810183-62849656 (+)
CBA/J MGP_CBAJ_G0018194
protein coding gene Chr11:67929187-67973220 (+)
DBA/2J MGP_DBA2J_G0018303
protein coding gene Chr11:60362955-60397860 (+)
FVB/NJ MGP_FVBNJ_G0018293
protein coding gene Chr11:60029398-60063920 (+)
LP/J MGP_LPJ_G0018375
protein coding gene Chr11:63691901-63728021 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018317
protein coding gene Chr11:68901924-68942078 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018900
protein coding gene Chr11:62844104-62878866 (+)
PWK/PhJ MGP_PWKPhJ_G0017550
protein coding gene Chr11:60976525-61017370 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017340
protein coding gene Chr11:62683691-62722849 (+)
WSB/EiJ MGP_WSBEiJ_G0017829
protein coding gene Chr11:62457330-62494438 (+)



Homology
more
  • Human Ortholog
    TEKT3, tektin 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEKT3, tektin 3
  • Synonyms
    SPGF81
  • Links
    NCBI Gene ID: 64518
    neXtProt AC: NX_Q9BXF9
    UniProt: Q9BXF9

  • Chr Location
    17p12; chr17:15303811-15343671 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human TEKT3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    1 images
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit defective sperm motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71062 NCBI Gene Model | MGI Sequence Detail 33302 C57BL/6J ±  kb
transcript NM_027660 RefSeq | MGI Sequence Detail 1739 C57BL/6 x 129  
polypeptide Q6X6Z7 UniProt | EBI | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 1
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Gene Ontology 10
    Phenotypes 4
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345053 Wang Y, et al., Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice. J Genet Genomics. 2023 Sep 13;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory