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Ccdc178 Gene Detail
Summary
  • Symbol
    Ccdc178
  • Name
    coiled coil domain containing 178
  • Synonyms
    4921528I01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918200
    NCBI Gene: 70950
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:21943954-22304453 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 11.96 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1783 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918200
 protein coding gene Chr18:21943950-22304499 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024189
 protein coding gene Chr18:19453622-19845950 (-)
A/J MGP_AJ_G0024154
 protein coding gene Chr18:18937448-19299600 (-)
AKR/J MGP_AKRJ_G0024123
 protein coding gene Chr18:19518459-19891034 (-)
BALB/cJ MGP_BALBcJ_G0024154
 protein coding gene Chr18:19004110-19369105 (-)
C3H/HeJ MGP_C3HHeJ_G0023922
 protein coding gene Chr18:19462441-19828633 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024596
 protein coding gene Chr18:20371895-20753859 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022038
 protein coding gene Chr18:18912606-19262562 (-)
CAST/EiJ MGP_CASTEiJ_G0023395
 protein coding gene Chr18:19238288-19619824 (-)
CBA/J MGP_CBAJ_G0023890
 protein coding gene Chr18:20913099-21302850 (-)
DBA/2J MGP_DBA2J_G0024022
 protein coding gene Chr18:18637215-18994000 (-)
FVB/NJ MGP_FVBNJ_G0023988
 protein coding gene Chr18:18416269-18769900 (-)
LP/J MGP_LPJ_G0024103
 protein coding gene Chr18:19620772-20006974 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024016
 protein coding gene Chr18:21775181-22216597 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024644
 protein coding gene Chr18:19282743-19658378 (-)
PWK/PhJ MGP_PWKPhJ_G0023140
 protein coding gene Chr18:18740444-19120415 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022949
 protein coding gene Chr18:19456322-19827424 (-)
WSB/EiJ MGP_WSBEiJ_G0023460
 protein coding gene Chr18:19198668-19580286 (-)



Homology
more
  • Human Ortholog
    CCDC178, coiled-coil domain containing 178
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC178, coiled-coil domain containing 178
  • Synonyms
    C18orf34
  • Links
    NCBI Gene ID: 374864
    neXtProt AC: NX_Q5BJE1
    UniProt: Q5BJE1

  • Chr Location
    18q12.1; chr18:32937402-33441101 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    3
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70950 NCBI Gene Model | MGI Sequence Detail 360500 C57BL/6J ±  kb
    transcript NM_027616 RefSeq | MGI Sequence Detail 3335 C57BL/6  
    polypeptide Q8CDV0 UniProt | EBI | MGI Sequence Detail 866 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 3

      Microarray probesets 2
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 1
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory