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Gpr173 Gene Detail
Summary
  • Symbol
    Gpr173
  • Name
    G-protein coupled receptor 173
  • Synonyms
    3230401K02Rik, SREB3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918021
    NCBI Gene: 70771
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:151126594-151151700 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 68.46 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918021
 protein coding gene ChrX:151126594-151151763 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036186
 protein coding gene ChrX:150109764-150134636 (-)
A/J MGP_AJ_G0036162
 protein coding gene ChrX:149295986-149321076 (-)
AKR/J MGP_AKRJ_G0036088
 protein coding gene ChrX:154137949-154163132 (-)
BALB/cJ MGP_BALBcJ_G0036153
 protein coding gene ChrX:147484666-147509477 (-)
C3H/HeJ MGP_C3HHeJ_G0035861
 protein coding gene ChrX:150322288-150347486 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036678
 protein coding gene ChrX:154382869-154408620 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033502
 protein coding gene ChrX:140985060-141010471 (-)
CAST/EiJ MGP_CASTEiJ_G0035152
 protein coding gene ChrX:129743745-129773053 (-)
CBA/J MGP_CBAJ_G0035838
 protein coding gene ChrX:158925796-158953205 (-)
DBA/2J MGP_DBA2J_G0035996
 protein coding gene ChrX:148356255-148381205 (-)
FVB/NJ MGP_FVBNJ_G0035930
 protein coding gene ChrX:147492082-147518796 (-)
LP/J MGP_LPJ_G0036087
 protein coding gene ChrX:151213544-151238531 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035966
 protein coding gene ChrX:167075140-167100646 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036713
 protein coding gene ChrX:149637119-149662003 (-)
PWK/PhJ MGP_PWKPhJ_G0034846
 protein coding gene ChrX:126680208-126707281 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034672
 protein coding gene ChrX:130197425-130223172 (-)
WSB/EiJ MGP_WSBEiJ_G0035287
 protein coding gene ChrX:147687683-147712737 (-)



Homology
more
  • Human Ortholog
    GPR173, G protein-coupled receptor 173
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR173, G protein-coupled receptor 173
  • Synonyms
    SREB3
  • Links
    NCBI Gene ID: 54328
    neXtProt AC: NX_Q9NS66
    UniProt: Q9NS66

  • Chr Location
    Xp11.22; chrX:53048789-53080615 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    833
  • Tissues
    20
  • cDNA Data
    8
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056679 Ensembl Gene Model | MGI Sequence Detail 25107 C57BL/6J ±  kb
transcript ENSMUST00000070316 Ensembl | MGI Sequence Detail 4855 Not Applicable  
polypeptide ENSMUSP00000065533 Ensembl | MGI Sequence Detail 373 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:342538 He L, et al., A Novel CCK Receptor GPR173 Mediates Potentiation of GABAergic Inhibition. J Neurosci. 2023 Mar 29;43(13):2305-2325
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory