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Myl6b Gene Detail
Summary
  • Symbol
    Myl6b
  • Name
    myosin, light polypeptide 6B
  • Synonyms
    5730437E04Rik, MGC:41229
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917789
    NCBI Gene: 216459
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128330026-128334554 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 76.77 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917789
 protein coding gene Chr10:128330026-128334554 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017868
 protein coding gene Chr10:132240245-132245727 (-)
A/J MGP_AJ_G0017843
 protein coding gene Chr10:126925760-126931806 (-)
AKR/J MGP_AKRJ_G0017806
 protein coding gene Chr10:130644531-130649105 (-)
BALB/cJ MGP_BALBcJ_G0017807
 protein coding gene Chr10:127306292-127310799 (-)
C3H/HeJ MGP_C3HHeJ_G0017630
 protein coding gene Chr10:130807914-130812410 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018262
 protein coding gene Chr10:136715740-136721115 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015940
 protein coding gene Chr10:120855631-120860113 (-)
CAST/EiJ MGP_CASTEiJ_G0017191
 protein coding gene Chr10:131524009-131528521 (-)
CBA/J MGP_CBAJ_G0017600
 protein coding gene Chr10:142283289-142289219 (-)
DBA/2J MGP_DBA2J_G0017706
 protein coding gene Chr10:125989805-125994928 (-)
FVB/NJ MGP_FVBNJ_G0017701
 protein coding gene Chr10:124911644-124917501 (-)
LP/J MGP_LPJ_G0017780
 protein coding gene Chr10:132827611-132834441 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017729
 protein coding gene Chr10:144864692-144870064 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018302
 protein coding gene Chr10:130752899-130758314 (-)
PWK/PhJ MGP_PWKPhJ_G0016976
 protein coding gene Chr10:126245592-126250747 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016765
 protein coding gene Chr10:129851386-129855834 (-)
WSB/EiJ MGP_WSBEiJ_G0017250
 protein coding gene Chr10:130966119-130972860 (-)



Homology
more
  • Human Ortholog
    MYL6B, myosin light chain 6B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYL6B, myosin light chain 6B
  • Synonyms
    MLC1SA
  • Links
    NCBI Gene ID: 140465
    neXtProt AC: NX_P14649
    UniProt: P14649

  • Chr Location
    12q13.2; chr12:56152256-56159647 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    803
  • Tissues
    9
  • cDNA Data
    28
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 216459 NCBI Gene Model | MGI Sequence Detail 4529 C57BL/6J ±  kb
transcript NM_172259 RefSeq | MGI Sequence Detail 1053 Not Specified  
polypeptide Q8CI43 UniProt | EBI | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    cDNA 29
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:113707 Hailstones DL, et al., Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function. Mol Cell Biol. 1990 Mar;10(3):1095-104
  • Latest
    J:273652 Chao CM, et al., Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia. Hum Mol Genet. 2019 May 1;28(9):1429-1444
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory