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Taf15 Gene Detail
Summary
  • Symbol
    Taf15
  • Name
    TATA-box binding protein associated factor 15
  • Synonyms
    2610111C21Rik, 68kDa, Taf2n, TAFII68
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917689
    NCBI Gene: 70439
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:83363912-83397569 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 50.49 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    77 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917689
 protein coding gene Chr11:83363897-83397569 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018850
 protein coding gene Chr11:84796648-84839017 (+)
A/J MGP_AJ_G0018817
 protein coding gene Chr11:81583465-81616888 (+)
AKR/J MGP_AKRJ_G0018787
 protein coding gene Chr11:84008517-84057530 (+)
BALB/cJ MGP_BALBcJ_G0018790
 protein coding gene Chr11:81994262-82027289 (+)
C3H/HeJ MGP_C3HHeJ_G0018604
 protein coding gene Chr11:84068394-84103387 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019242
 protein coding gene Chr11:87394328-87432947 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016876
 protein coding gene Chr11:78710134-78745513 (+)
CAST/EiJ MGP_CASTEiJ_G0018159
 protein coding gene Chr11:84644173-84688451 (+)
CBA/J MGP_CBAJ_G0018575
 protein coding gene Chr11:91176773-91212570 (+)
DBA/2J MGP_DBA2J_G0018683
 protein coding gene Chr11:81179728-81217304 (+)
FVB/NJ MGP_FVBNJ_G0018672
 protein coding gene Chr11:80662481-80700793 (+)
LP/J MGP_LPJ_G0018753
 protein coding gene Chr11:85360422-85397047 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0019282
 protein coding gene Chr11:84281205-84320396 (+)
PWK/PhJ MGP_PWKPhJ_G0017928
 protein coding gene Chr11:81940933-81975497 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017720
 protein coding gene Chr11:83818791-83856346 (+)
WSB/EiJ MGP_WSBEiJ_G0018210
 protein coding gene Chr11:84144106-84181984 (+)



Homology
more
  • Human Ortholog
    TAF15, TATA-box binding protein associated factor 15
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAF15, TATA-box binding protein associated factor 15
  • Synonyms
    Npl3, RBP56, TAF2N, TAFII68
  • Links
    NCBI Gene ID: 8148
    neXtProt AC: NX_Q92804
    UniProt: Q92804

  • Chr Location
    17q12; chr17:35809482-35864615 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human TAF15 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    785
  • Tissues
    55
  • cDNA Data
    36
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020680 Ensembl Gene Model | MGI Sequence Detail 33658 C57BL/6J ±  kb
    transcript ENSMUST00000021018 Ensembl | MGI Sequence Detail 2068 Not Applicable  
    polypeptide ENSMUSP00000021018 Ensembl | MGI Sequence Detail 557 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
      IPR035979 RNA-binding domain superfamily
      IPR000504 RNA recognition motif domain
      IPR034870 TAF15/EWS/TLS family
      IPR001876 Zinc finger, RanBP2-type
      IPR036443 Zinc finger, RanBP2-type superfamily
    Molecular
    Reagents
    less
    • All nucleic 40
      Genomic 1
      cDNA 38
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 8
      Gene Ontology 3
      Phenotypes 21
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:284994 Gasperini L, et al., The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization. Mol Biol Cell. 2018 Oct 24;:mbcE18020108
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory