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Kcnip1 Gene Detail
Summary
  • Symbol
    Kcnip1
  • Name
    Kv channel-interacting protein 1
  • Synonyms
    2900046L02Rik, 3202002F18Rik, KCHIP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917607
    NCBI Gene: 70357
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:33579339-33943152 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 19.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    891 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917607
 protein coding gene Chr11:33579339-33943854 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018147
 protein coding gene Chr11:31942691-32325813 (-)
A/J MGP_AJ_G0018120
 protein coding gene Chr11:30726254-31096735 (-)
AKR/J MGP_AKRJ_G0018084
 protein coding gene Chr11:31685004-32060148 (-)
BALB/cJ MGP_BALBcJ_G0018089
 protein coding gene Chr11:30898979-31276544 (-)
C3H/HeJ MGP_C3HHeJ_G0017902
 protein coding gene Chr11:31627192-32012006 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018543
 protein coding gene Chr11:32974418-33360726 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016198
 protein coding gene Chr11:29223484-29581983 (-)
CAST/EiJ MGP_CASTEiJ_G0017466
 protein coding gene Chr11:31717552-32119126 (-)
CBA/J MGP_CBAJ_G0017875
 protein coding gene Chr11:34582481-35015841 (-)
DBA/2J MGP_DBA2J_G0017985
 protein coding gene Chr11:30494347-30864226 (-)
FVB/NJ MGP_FVBNJ_G0017979
 protein coding gene Chr11:30317582-30686896 (-)
LP/J MGP_LPJ_G0018057
 protein coding gene Chr11:32211273-32597990 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018003
 protein coding gene Chr11:35527732-35916175 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018582
 protein coding gene Chr11:31835315-32219142 (-)
PWK/PhJ MGP_PWKPhJ_G0017247
 protein coding gene Chr11:30682223-31055017 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017039
 protein coding gene Chr11:31548869-31952145 (-)
WSB/EiJ MGP_WSBEiJ_G0017515
 protein coding gene Chr11:31457214-31852170 (-)



Homology
more
  • Human Ortholog
    KCNIP1, potassium voltage-gated channel interacting protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCNIP1, potassium voltage-gated channel interacting protein 1
  • Synonyms
    KCHIP1, VABP
  • Links
    NCBI Gene ID: 30820
    neXtProt AC: NX_Q9NZI2
    UniProt: Q9NZI2

  • Chr Location
    5q35.1; chr5:170353487-170736632 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increase susceptibility to pentylenetetrazole-induced seizures.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    987
  • Tissues
    87
  • cDNA Data
    19
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053519 Ensembl Gene Model | MGI Sequence Detail 363814 C57BL/6J ±  kb
transcript ENSMUST00000238436 Ensembl | MGI Sequence Detail 699 Not Applicable  
polypeptide ENSMUSP00000158813 Ensembl | MGI Sequence Detail 232 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 23
    Primer pair 4

    Microarray probesets 6
Other
Accession IDs
less
MGI:1920202, MGI:2144283, MGI:2144547
References
more
  • Summaries
    All 45
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:343283 Russell NX, et al., Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea. Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1;325(6):L788-L802
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory