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Prrg1 Gene Detail
Summary
  • Symbol
    Prrg1
  • Name
    proline rich Gla (G-carboxyglutamic acid) 1
  • Synonyms
    2010007L08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917364
    NCBI Gene: 546336
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:77493219-77627502 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 38.34 cM, cytoband A7.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917364
protein coding gene ChrX:77493216-77627539 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035879
protein coding gene ChrX:74320636-74461415 (-)
A/J MGP_AJ_G0035865
protein coding gene ChrX:74589245-74718133 (-)
AKR/J MGP_AKRJ_G0035783
protein coding gene ChrX:76537206-76672900 (-)
BALB/cJ MGP_BALBcJ_G0035845
protein coding gene ChrX:73511574-73645626 (-)
C3H/HeJ MGP_C3HHeJ_G0035556
protein coding gene ChrX:74750767-74899965 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036377
protein coding gene ChrX:76625657-76763767 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033207
protein coding gene ChrX:73972072-74100572 (-)
CAST/EiJ MGP_CASTEiJ_G0034844
protein coding gene ChrX:60002947-60143305 (-)
CBA/J MGP_CBAJ_G0035530
protein coding gene ChrX:78674234-78844644 (-)
DBA/2J MGP_DBA2J_G0035686
protein coding gene ChrX:74010133-74152264 (-)
FVB/NJ MGP_FVBNJ_G0035625
protein coding gene ChrX:73248006-73378919 (-)
LP/J MGP_LPJ_G0035774
protein coding gene ChrX:75167957-75306547 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035662
protein coding gene ChrX:81493624-81630374 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036403
protein coding gene ChrX:74130931-74263730 (-)
PWK/PhJ MGP_PWKPhJ_G0034542
protein coding gene ChrX:58065444-58208056 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034373
protein coding gene ChrX:60899629-61044182 (-)
WSB/EiJ MGP_WSBEiJ_G0034983
protein coding gene ChrX:73315526-73451124 (-)



Homology
more
  • Human Ortholog
    PRRG1, proline rich and Gla domain 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRRG1, proline rich and Gla domain 1
  • Synonyms
    PRGP1
  • Links
    NCBI Gene ID: 5638
    neXtProt AC: NX_O14668
    UniProt: O14668

  • Chr Location
    Xp21.1; chrX:37349309-37457292 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047996 Ensembl Gene Model | MGI Sequence Detail 134284 C57BL/6J ±  kb
transcript ENSMUST00000114025 Ensembl | MGI Sequence Detail 3964 Not Applicable  
polypeptide ENSMUSP00000109659 Ensembl | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR017857 Coagulation factor-like, Gla domain superfamily
    IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domain
    IPR035972 Gamma-carboxyglutamic acid-rich (GLA) domain superfamily
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 4
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory