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Spaca9 Gene Detail
Summary
  • Symbol
    Spaca9
  • Name
    sperm acrosome associated 9
  • Synonyms
    1700026L06Rik, Mast
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917237
    NCBI Gene: 69987
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:28582092-28589663 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 19.38 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917237
protein coding gene Chr2:28582092-28589739 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025530
protein coding gene Chr2:26769353-26776935 (-)
A/J MGP_AJ_G0025507
protein coding gene Chr2:25745568-25753394 (-)
AKR/J MGP_AKRJ_G0025477
protein coding gene Chr2:26597714-26605317 (-)
BALB/cJ MGP_BALBcJ_G0025503
protein coding gene Chr2:25866216-25874147 (-)
C3H/HeJ MGP_C3HHeJ_G0025264
protein coding gene Chr2:26520142-26527754 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025947
protein coding gene Chr2:27662824-27671254 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023357
protein coding gene Chr2:24561608-24570758 (-)
CAST/EiJ MGP_CASTEiJ_G0024727
protein coding gene Chr2:26425986-26433675 (-)
CBA/J MGP_CBAJ_G0025242
protein coding gene Chr2:28592600-28600197 (-)
DBA/2J MGP_DBA2J_G0025375
protein coding gene Chr2:25556101-25563685 (-)
FVB/NJ MGP_FVBNJ_G0025337
protein coding gene Chr2:25343180-25350798 (-)
LP/J MGP_LPJ_G0025461
protein coding gene Chr2:26714641-26723100 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025368
protein coding gene Chr2:28617774-28626369 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026006
protein coding gene Chr2:26516918-26524562 (-)
PWK/PhJ MGP_PWKPhJ_G0024474
protein coding gene Chr2:25364538-25372255 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024274
protein coding gene Chr2:26647470-26655144 (-)
WSB/EiJ MGP_WSBEiJ_G0024796
protein coding gene Chr2:26650547-26659510 (-)



Homology
more
  • Human Ortholog
    SPACA9, sperm acrosome associated 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPACA9, sperm acrosome associated 9
  • Synonyms
    C9orf9, Mast
  • Links
    NCBI Gene ID: 11092
    neXtProt AC: NX_Q96E40
    UniProt: Q96E40

  • Chr Location
    9q34.13; chr9:132878027-132890314 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a null allele exhibit normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69987 NCBI Gene Model | MGI Sequence Detail 7572 C57BL/6J ±  kb
transcript NM_027283 RefSeq | MGI Sequence Detail 901 Not Specified  
polypeptide Q7TPM5 UniProt | EBI | MGI Sequence Detail 168 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 46
    cDNA 44
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:319865 Castaneda JM, et al., FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice. J Cell Sci. 2021 Nov 1;134(21):jcs259206

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory