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Cmbl Gene Detail
Summary
  • Symbol
    Cmbl
  • Name
    carboxymethylenebutenolidase homolog
  • Synonyms
    2310016A09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916824
    NCBI Gene: 69574
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:31565535-31590265 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 13.00 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    205 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916824
 protein coding gene Chr15:31565314-31590266 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021767
 protein coding gene Chr15:29823361-29848094 (+)
A/J MGP_AJ_G0021728
 protein coding gene Chr15:28621783-28644724 (+)
AKR/J MGP_AKRJ_G0021705
 protein coding gene Chr15:29354203-29375900 (+)
BALB/cJ MGP_BALBcJ_G0021734
 protein coding gene Chr15:28629825-28651560 (+)
C3H/HeJ MGP_C3HHeJ_G0021509
 protein coding gene Chr15:29375337-29398392 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022173
 protein coding gene Chr15:31017348-31037866 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019711
 protein coding gene Chr15:26719474-26737805 (+)
CAST/EiJ MGP_CASTEiJ_G0021025
 protein coding gene Chr15:29867460-29891668 (+)
CBA/J MGP_CBAJ_G0021478
 protein coding gene Chr15:31897033-31919058 (+)
DBA/2J MGP_DBA2J_G0021602
 protein coding gene Chr15:28430176-28451796 (+)
FVB/NJ MGP_FVBNJ_G0021580
 protein coding gene Chr15:27952113-27974567 (+)
LP/J MGP_LPJ_G0021671
 protein coding gene Chr15:29691088-29717926 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021605
 protein coding gene Chr15:34875819-34897046 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022196
 protein coding gene Chr15:29597961-29631159 (+)
PWK/PhJ MGP_PWKPhJ_G0020769
 protein coding gene Chr15:28593869-28614306 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020607
 protein coding gene Chr15:29395880-29417660 (+)
WSB/EiJ MGP_WSBEiJ_G0021081
 protein coding gene Chr15:29556902-29577718 (+)



Homology
more
  • Human Ortholog
    CMBL, carboxymethylenebutenolidase homolog
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CMBL, carboxymethylenebutenolidase homolog
  • Synonyms
    JS-1
  • Links
    NCBI Gene ID: 134147
    neXtProt AC: NX_Q96DG6
    UniProt: Q96DG6

  • Chr Location
    5p15.2; chr5:10275875-10307902 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    877
  • Tissues
    100
  • cDNA Data
    53
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022235 Ensembl Gene Model | MGI Sequence Detail 24731 C57BL/6J ±  kb
transcript ENSMUST00000070918 Ensembl | MGI Sequence Detail 1155 Not Applicable  
polypeptide ENSMUSP00000070314 Ensembl | MGI Sequence Detail 245 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 53

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory