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Gtpbp4 Gene Detail
Summary
  • Symbol
    Gtpbp4
  • Name
    GTP binding protein 4
  • Synonyms
    2610028C09Rik, Crfg, Nog1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916487
    NCBI Gene: 69237
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:9016367-9046119 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 3.64 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    299 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916487
 protein coding gene Chr13:9016039-9046119 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020222
 protein coding gene Chr13:5595307-5619250 (-)
A/J MGP_AJ_G0020178
 protein coding gene Chr13:5592103-5616299 (-)
AKR/J MGP_AKRJ_G0020153
 protein coding gene Chr13:5649897-5674173 (-)
BALB/cJ MGP_BALBcJ_G0020161
 protein coding gene Chr13:5590303-5614482 (-)
C3H/HeJ MGP_C3HHeJ_G0019965
 protein coding gene Chr13:5778004-5802871 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020608
 protein coding gene Chr13:5955267-5980201 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018215
 protein coding gene Chr13:5530164-5554559 (-)
CAST/EiJ MGP_CASTEiJ_G0019503
 protein coding gene Chr13:5488390-5514180 (-)
CBA/J MGP_CBAJ_G0019932
 protein coding gene Chr13:6075152-6109285 (-)
DBA/2J MGP_DBA2J_G0020049
 protein coding gene Chr13:5422596-5447973 (-)
FVB/NJ MGP_FVBNJ_G0020034
 protein coding gene Chr13:5278447-5304424 (-)
LP/J MGP_LPJ_G0020123
 protein coding gene Chr13:5701956-5726098 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020070
 protein coding gene Chr13:6404516-6428864 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020636
 protein coding gene Chr13:5603623-5627655 (-)
PWK/PhJ MGP_PWKPhJ_G0019266
 protein coding gene Chr13:5441586-5469658 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019073
 protein coding gene Chr13:5605394-5633936 (-)
WSB/EiJ MGP_WSBEiJ_G0019563
 protein coding gene Chr13:5511454-5538269 (-)



Homology
more
  • Human Ortholog
    GTPBP4, GTP binding protein 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GTPBP4, GTP binding protein 4
  • Synonyms
    CRFG, NGB, NOG1
  • Links
    NCBI Gene ID: 23560
    neXtProt AC: NX_Q9BZE4
    UniProt: Q9BZE4

  • Chr Location
    10p15.3; chr10:988434-1019932 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    45
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021149 Ensembl Gene Model | MGI Sequence Detail 29753 C57BL/6J ±  kb
transcript ENSMUST00000222098 Ensembl | MGI Sequence Detail 8783 Not Applicable  
polypeptide ENSMUSP00000152412 Ensembl | MGI Sequence Detail 634 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 5
Other
Accession IDs
less
MGI:1927543
References
more
  • Summaries
    All 40
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:64988 Burmester T, et al., A vertebrate globin expressed in the brain. Nature. 2000 Sep 28;407(6803):520-3
  • Latest
    J:344745 Xue Q, et al., NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3. PLoS Pathog. 2023 Jul;19(7):e1011511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory