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Pdia2 Gene Detail
Summary
  • Symbol
    Pdia2
  • Name
    protein disulfide isomerase associated 2
  • Synonyms
    1810041F13Rik, Pdip, Pdipl
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916441
    NCBI Gene: 69191
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26414973-26418061 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 13.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916441
 protein coding gene Chr17:26414973-26418108 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023393
 protein coding gene Chr17:25343171-25346259 (-)
A/J MGP_AJ_G0023352
 protein coding gene Chr17:24587211-24590299 (-)
AKR/J MGP_AKRJ_G0023318
 protein coding gene Chr17:24698260-24701348 (-)
BALB/cJ MGP_BALBcJ_G0023357
 protein coding gene Chr17:24808485-24811573 (-)
C3H/HeJ MGP_C3HHeJ_G0023117
 protein coding gene Chr17:25090499-25093587 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023799
 protein coding gene Chr17:26406819-26409907 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021275
 protein coding gene Chr17:22046200-22049297 (-)
CAST/EiJ MGP_CASTEiJ_G0022619
 protein coding gene Chr17:24998269-25001357 (-)
CBA/J MGP_CBAJ_G0023092
 protein coding gene Chr17:27342885-27345973 (-)
DBA/2J MGP_DBA2J_G0023222
 protein coding gene Chr17:24180537-24183625 (-)
FVB/NJ MGP_FVBNJ_G0023192
 protein coding gene Chr17:23943010-23946098 (-)
LP/J MGP_LPJ_G0023299
 protein coding gene Chr17:25621828-25624916 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023211
 protein coding gene Chr17:26912923-26916011 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023839
 protein coding gene Chr17:25048680-25051768 (-)
PWK/PhJ MGP_PWKPhJ_G0022368
 protein coding gene Chr17:22950971-22954059 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022186
 protein coding gene Chr17:23115497-23118582 (-)
WSB/EiJ MGP_WSBEiJ_G0022682
 protein coding gene Chr17:25070096-25073184 (-)



Homology
more
  • Human Ortholog
    PDIA2, protein disulfide isomerase family A member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PDIA2, protein disulfide isomerase family A member 2
  • Synonyms
    PDA2, PDI, PDIP, PDIR
  • Links
    NCBI Gene ID: 64714
    neXtProt AC: NX_Q13087
    UniProt: Q13087

  • Chr Location
    16p13.3; chr16:283164-287215 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    16
  • cDNA Data
    35
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024184 Ensembl Gene Model | MGI Sequence Detail 3089 C57BL/6J ±  kb
transcript ENSMUST00000039113 Ensembl | MGI Sequence Detail 1721 Not Applicable  
polypeptide ENSMUSP00000035584 Ensembl | MGI Sequence Detail 527 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 36

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146905, MGI:891973
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:39375 Desilva MG, et al., Molecular characterization of a pancreas-specific protein disulfide isomerase, PDIp. DNA Cell Biol. 1997 Mar;16(3):269-74
  • Latest
    J:333870 Jazwiec PA, et al., Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism. Biol Reprod. 2022 Aug 9;107(2):574-589
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory