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Caly Gene Detail
Summary
  • Symbol
    Caly
  • Name
    calcyon neuron-specific vesicular protein
  • Synonyms
    0710001P07Rik, 1110004A22Rik, Calcyon, Drd1ip
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915816
    NCBI Gene: 68566
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:139649793-139662461 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 85.07 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    55 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915816
 protein coding gene Chr7:139649793-139662485 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033161
 protein coding gene Chr7:145147718-145160386 (-)
A/J MGP_AJ_G0033143
 protein coding gene Chr7:141020128-141032803 (-)
AKR/J MGP_AKRJ_G0033075
 protein coding gene Chr7:144856324-144868974 (-)
BALB/cJ MGP_BALBcJ_G0033144
 protein coding gene Chr7:140750992-140763651 (-)
C3H/HeJ MGP_C3HHeJ_G0032858
 protein coding gene Chr7:144664415-144677083 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033655
 protein coding gene Chr7:150486909-150499569 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030628
 protein coding gene Chr7:142141272-142154065 (-)
CAST/EiJ MGP_CASTEiJ_G0032188
 protein coding gene Chr7:136959262-136973610 (-)
CBA/J MGP_CBAJ_G0032831
 protein coding gene Chr7:155550870-155566391 (-)
DBA/2J MGP_DBA2J_G0032983
 protein coding gene Chr7:138981062-138993738 (-)
FVB/NJ MGP_FVBNJ_G0032936
 protein coding gene Chr7:138869766-138882446 (-)
LP/J MGP_LPJ_G0033077
 protein coding gene Chr7:146689933-146702587 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032968
 protein coding gene Chr7:156217619-156230378 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033675
 protein coding gene Chr7:143863498-143876166 (-)
PWK/PhJ MGP_PWKPhJ_G0031894
 protein coding gene Chr7:132162905-132176031 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031739
 protein coding gene Chr7:130697234-130711559 (-)
WSB/EiJ MGP_WSBEiJ_G0032299
 protein coding gene Chr7:144755012-144767778 (-)



Homology
more
  • Human Ortholog
    CALY, calcyon neuron specific vesicular protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CALY, calcyon neuron specific vesicular protein
  • Synonyms
    DRD1IP, NSG3
  • Links
    NCBI Gene ID: 50632
    neXtProt AC: NX_Q9NYX4
    UniProt: Q9NYX4

  • Chr Location
    10q26.3; chr10:133324072-133336935 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CALY associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    1 involving Caly
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    12 strains or lines available
Neurons in homozygous null mice have defects in clathrin-mediated endocytosis (CME) that manifests as an absence of long term depression in post-synaptic currents of the hippocampus.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    905
  • Tissues
    28
  • cDNA Data
    17
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025468 Ensembl Gene Model | MGI Sequence Detail 12669 C57BL/6J ±  kb
transcript ENSMUST00000026541 Ensembl | MGI Sequence Detail 1220 Not Applicable  
polypeptide ENSMUSP00000026541 Ensembl | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 2
Other
Accession IDs
less
MGI:1923521
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:197462 Dillman AA, et al., mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Nat Neurosci. 2013 Apr;16(4):499-506
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory