About   Help   FAQ
Dynll2 Gene Detail
Summary
  • Symbol
    Dynll2
  • Name
    dynein light chain LC8-type 2
  • Synonyms
    1700064A15Rik, 6720463E02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915347
    NCBI Gene: 68097
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:87870351-87878359 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 52.35 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915347
 protein coding gene Chr11:87870351-87892746 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018918
 protein coding gene Chr11:89648334-89656320 (-)
A/J MGP_AJ_G0018886
 protein coding gene Chr11:86181540-86189526 (-)
AKR/J MGP_AKRJ_G0018856
 protein coding gene Chr11:88796380-88806570 (-)
BALB/cJ MGP_BALBcJ_G0018859
 protein coding gene Chr11:86583355-86591341 (-)
C3H/HeJ MGP_C3HHeJ_G0018673
 protein coding gene Chr11:88819348-88827334 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019311
 protein coding gene Chr11:92378265-92386315 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016942
 protein coding gene Chr11:83200867-83208617 (-)
CAST/EiJ MGP_CASTEiJ_G0018228
 protein coding gene Chr11:89507248-89515239 (-)
CBA/J MGP_CBAJ_G0018644
 protein coding gene Chr11:96282080-96290067 (-)
DBA/2J MGP_DBA2J_G0018752
 protein coding gene Chr11:85742544-85750530 (-)
FVB/NJ MGP_FVBNJ_G0018741
 protein coding gene Chr11:85242295-85250282 (-)
LP/J MGP_LPJ_G0018822
 protein coding gene Chr11:90160333-90168320 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018768
 protein coding gene Chr11:96301529-96310322 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019351
 protein coding gene Chr11:89017662-89025642 (-)
PWK/PhJ MGP_PWKPhJ_G0017998
 protein coding gene Chr11:86593342-86601428 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017789
 protein coding gene Chr11:88576985-88584880 (-)
WSB/EiJ MGP_WSBEiJ_G0018277
 protein coding gene Chr11:88903769-88911558 (-)



Homology
more
  • Human Ortholog
    DYNLL2, dynein light chain LC8-type 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DYNLL2, dynein light chain LC8-type 2
  • Synonyms
    Dlc2, DNCL1B, RSPH22
  • Links
    NCBI Gene ID: 140735
    neXtProt AC: NX_Q96FJ2
    UniProt: Q96FJ2

  • Chr Location
    17q22; chr17:58083419-58095542 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    53
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    47
  • Targeted
    3
  • Genomic Mutations
    4 involving Dynll2
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    842
  • Tissues
    20
  • cDNA Data
    14
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020483 Ensembl Gene Model | MGI Sequence Detail 8009 C57BL/6J ±  kb
transcript ENSMUST00000107923 Ensembl | MGI Sequence Detail 2443 Not Applicable  
polypeptide ENSMUSP00000103556 Ensembl | MGI Sequence Detail 89 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1920652, MGI:2144689
References
more
  • Summaries
    All 57
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 9
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:334512 He S, et al., Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory