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Ccdc127 Gene Detail
Summary
  • Symbol
    Ccdc127
  • Name
    coiled-coil domain containing 127
  • Synonyms
    0610011N22Rik, 5430420E17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914683
    NCBI Gene: 67433
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:74498436-74513902 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 40.17 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    86 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914683
 protein coding gene Chr13:74498428-74513902 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020764
 protein coding gene Chr13:74851140-74867109 (+)
A/J MGP_AJ_G0020720
 protein coding gene Chr13:72178819-72194353 (+)
AKR/J MGP_AKRJ_G0020694
 protein coding gene Chr13:74435844-74451802 (+)
BALB/cJ MGP_BALBcJ_G0020717
 protein coding gene Chr13:72672278-72687708 (+)
C3H/HeJ MGP_C3HHeJ_G0020511
 protein coding gene Chr13:74123702-74140092 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021154
 protein coding gene Chr13:77333634-77351707 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018721
 protein coding gene Chr13:69008944-69024190 (+)
CAST/EiJ MGP_CASTEiJ_G0020028
 protein coding gene Chr13:73208469-73223914 (+)
CBA/J MGP_CBAJ_G0020470
 protein coding gene Chr13:80207598-80224950 (+)
DBA/2J MGP_DBA2J_G0020595
 protein coding gene Chr13:71997235-72012708 (+)
FVB/NJ MGP_FVBNJ_G0020575
 protein coding gene Chr13:71020452-71036046 (+)
LP/J MGP_LPJ_G0020668
 protein coding gene Chr13:75086762-75102247 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020603
 protein coding gene Chr13:78610533-78626418 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021193
 protein coding gene Chr13:73756523-73772356 (+)
PWK/PhJ MGP_PWKPhJ_G0019782
 protein coding gene Chr13:70739590-70752050 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019605
 protein coding gene Chr13:70248031-70265640 (+)
WSB/EiJ MGP_WSBEiJ_G0020086
 protein coding gene Chr13:74312381-74327703 (+)



Homology
more
  • Human Ortholog
    CCDC127, coiled-coil domain containing 127
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC127, coiled-coil domain containing 127
  • Links
    NCBI Gene ID: 133957
    neXtProt AC: NX_Q96BQ5
    UniProt: Q96BQ5

  • Chr Location
    5p15.33; chr5:196868-218153 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67433 NCBI Gene Model | MGI Sequence Detail 15467 C57BL/6J ±  kb
    transcript NM_001168658 RefSeq | MGI Sequence Detail 5764 C57BL/6  
    polypeptide Q3TC33 UniProt | EBI | MGI Sequence Detail 260 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1918606, MGI:2145196, MGI:2145408
    References
    more
    • Summaries
      All 36
      Phenotypes 13
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory