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Gemin6 Gene Detail
Summary
  • Symbol
    Gemin6
  • Name
    gem nuclear organelle associated protein 6
  • Synonyms
    2610019B15Rik, 2810470M17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914492
    NCBI Gene: 67242
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:80531870-80535926 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 50.63 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914492
 protein coding gene Chr17:80514933-80535926 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024059
 protein coding gene Chr17:83134283-83138339 (+)
A/J MGP_AJ_G0024016
 protein coding gene Chr17:80578718-80582792 (+)
AKR/J MGP_AKRJ_G0023985
 protein coding gene Chr17:81837348-81841415 (+)
BALB/cJ MGP_BALBcJ_G0024018
 protein coding gene Chr17:80456223-80460450 (+)
C3H/HeJ MGP_C3HHeJ_G0023782
 protein coding gene Chr17:82716818-82720865 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024462
 protein coding gene Chr17:86166304-86174325 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030803
 protein coding gene Chr8:1794898-1796196 (-)
CAST/EiJ MGP_CASTEiJ_G0023262
 protein coding gene Chr17:83392927-83400161 (+)
CBA/J MGP_CBAJ_G0023756
 protein coding gene Chr17:89749320-89753349 (+)
DBA/2J MGP_DBA2J_G0023885
 protein coding gene Chr17:79087756-79091805 (+)
FVB/NJ MGP_FVBNJ_G0023851
 protein coding gene Chr17:78588170-78592226 (+)
LP/J MGP_LPJ_G0023968
 protein coding gene Chr17:83974770-83978828 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023879
 protein coding gene Chr17:89802518-89807191 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024507
 protein coding gene Chr17:82319668-82341094 (+)
PWK/PhJ MGP_PWKPhJ_G0023008
 protein coding gene Chr17:78623637-78627919 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022819
 protein coding gene Chr17:79099854-79103929 (+)
WSB/EiJ MGP_WSBEiJ_G0023329
 protein coding gene Chr17:83139999-83144995 (+)



Homology
more
  • Human Ortholog
    GEMIN6, gem nuclear organelle associated protein 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GEMIN6, gem nuclear organelle associated protein 6
  • Links
    NCBI Gene ID: 79833
    neXtProt AC: NX_Q8WXD5
    UniProt: Q8WXD5

  • Chr Location
    2p22.1; chr2:38751534-38785002 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    6
  • cDNA Data
    44
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055760 Ensembl Gene Model | MGI Sequence Detail 4057 C57BL/6J ±  kb
transcript ENSMUST00000069486 Ensembl | MGI Sequence Detail 1134 Not Applicable  
polypeptide ENSMUSP00000063554 Ensembl | MGI Sequence Detail 166 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 44
    cDNA 44

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916458
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:319558 Bizen N, et al., Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. Cell Death Differ. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory