About   Help   FAQ
Snrnp27 Gene Detail
Summary
  • Symbol
    Snrnp27
  • Name
    small nuclear ribonucleoprotein 27 (U4/U6.U5)
  • Synonyms
    2610209M04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913868
    NCBI Gene: 66618
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:86652151-86661473 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.75 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913868
protein coding gene Chr6:86652133-86661504 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030981
protein coding gene Chr6:87981391-87991942 (-)
A/J MGP_AJ_G0030947
protein coding gene Chr6:84581031-84590523 (-)
AKR/J MGP_AKRJ_G0030878
protein coding gene Chr6:87029460-87038832 (-)
BALB/cJ MGP_BALBcJ_G0030960
protein coding gene Chr6:84592873-84602245 (-)
C3H/HeJ MGP_C3HHeJ_G0030750
protein coding gene Chr6:97425549-97435096 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031417
protein coding gene Chr6:90362791-90372162 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028601
protein coding gene Chr6:82764469-82773533 (-)
CAST/EiJ MGP_CASTEiJ_G0030069
protein coding gene Chr6:87100525-87109892 (-)
CBA/J MGP_CBAJ_G0030644
protein coding gene Chr6:93914160-93926358 (-)
DBA/2J MGP_DBA2J_G0030800
protein coding gene Chr6:83898507-83908740 (-)
FVB/NJ MGP_FVBNJ_G0030753
protein coding gene Chr6:83081868-83091366 (-)
LP/J MGP_LPJ_G0030877
protein coding gene Chr6:88012331-88023032 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030786
protein coding gene Chr6:98032389-98042856 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031444
protein coding gene Chr6:86867422-86876794 (-)
PWK/PhJ MGP_PWKPhJ_G0029784
protein coding gene Chr6:82840506-82849871 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029612
protein coding gene Chr6:85706951-85716809 (-)
WSB/EiJ MGP_WSBEiJ_G0030150
protein coding gene Chr6:87334071-87343442 (-)



Homology
more
  • Human Ortholog
    SNRNP27, small nuclear ribonucleoprotein U4/U6.U5 subunit 27
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNRNP27, small nuclear ribonucleoprotein U4/U6.U5 subunit 27
  • Synonyms
    27K, RY1
  • Links
    NCBI Gene ID: 11017
    neXtProt AC: NX_Q8WVK2
    UniProt: Q8WVK2

  • Chr Location
    2p13.3; chr2:69893956-69905575 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66618 NCBI Gene Model | MGI Sequence Detail 9323 C57BL/6J ±  kb
    transcript NM_025665 RefSeq | MGI Sequence Detail 836 C57BL/6  
    polypeptide Q8K194 UniProt | EBI | MGI Sequence Detail 155 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000015334 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
    • InterPro Domains
      IPR013957 U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein
    Molecular
    Reagents
    less
    • All nucleic 78
      cDNA 78

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1889831, MGI:2141570
    References
    more
    • Summaries
      All 38
      Gene Ontology 3
      Phenotypes 14
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.
    last database update
    03/19/2024
    MGI 6.23
    The Jackson Laboratory