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Sys1 Gene Detail
Summary
  • Symbol
    Sys1
  • Name
    SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
  • Synonyms
    2610042O14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913710
    NCBI Gene: 66460
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164298884-164321558 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.16 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913710
 protein coding gene Chr2:164297736-164322141 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026852
 protein coding gene Chr2:169900035-169923696 (+)
A/J MGP_AJ_G0026818
 protein coding gene Chr2:162984768-163008540 (+)
AKR/J MGP_AKRJ_G0026789
 protein coding gene Chr2:167825956-167848851 (+)
BALB/cJ MGP_BALBcJ_G0026827
 protein coding gene Chr2:163346937-163370857 (+)
C3H/HeJ MGP_C3HHeJ_G0026569
 protein coding gene Chr2:168181112-168203454 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027275
 protein coding gene Chr2:174815640-174854137 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024645
 protein coding gene Chr2:156396876-156418460 (+)
CAST/EiJ MGP_CASTEiJ_G0026029
 protein coding gene Chr2:168602795-168625937 (+)
CBA/J MGP_CBAJ_G0026546
 protein coding gene Chr2:181158549-181190227 (+)
DBA/2J MGP_DBA2J_G0026684
 protein coding gene Chr2:162156807-162179290 (+)
FVB/NJ MGP_FVBNJ_G0026650
 protein coding gene Chr2:160569037-160591486 (+)
LP/J MGP_LPJ_G0026787
 protein coding gene Chr2:169981205-170005610 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026670
 protein coding gene Chr2:184755896-184780973 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027331
 protein coding gene Chr2:167729089-167752025 (+)
PWK/PhJ MGP_PWKPhJ_G0025764
 protein coding gene Chr2:161732728-161756389 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025565
 protein coding gene Chr2:166600478-166626238 (+)
WSB/EiJ MGP_WSBEiJ_G0026100
 protein coding gene Chr2:168588019-168613189 (+)



Homology
more
  • Human Ortholog
    SYS1, SYS1 golgi trafficking protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYS1, SYS1 golgi trafficking protein
  • Synonyms
    C20orf169, dJ453C12.4, dJ453C12.4.1
  • Links
    NCBI Gene ID: 90196
    neXtProt AC: NX_Q8N2H4
    UniProt: Q8N2H4

  • Chr Location
    20q13.12; chr20:45361937-45376798 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    23
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045503 Ensembl Gene Model | MGI Sequence Detail 22675 C57BL/6J ±  kb
transcript ENSMUST00000072452 Ensembl | MGI Sequence Detail 1606 Not Applicable  
polypeptide ENSMUSP00000072275 Ensembl | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 10
Other
Accession IDs
less
MGI:2138874, MGI:2139531
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:255335 Tan GH, et al., PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum. Cell Res. 2018 Jan;28(1):90-110
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory