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Mrps36 Gene Detail
Summary
  • Symbol
    Mrps36
  • Name
    mitochondrial ribosomal protein S36
  • Synonyms
    1110018B13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913378
    NCBI Gene: 66128
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:100872463-100881167 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 53.23 cM, cytoband D1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913378
 protein coding gene Chr13:100872448-100881167 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020893
 protein coding gene Chr13:102670094-102678248 (-)
A/J MGP_AJ_G0020844
 protein coding gene Chr13:98680731-98689597 (-)
AKR/J MGP_AKRJ_G0020819
 protein coding gene Chr13:101706312-101714867 (-)
BALB/cJ MGP_BALBcJ_G0020844
 protein coding gene Chr13:99406716-99419763 (-)
C3H/HeJ MGP_C3HHeJ_G0020633
 protein coding gene Chr13:101415490-101423436 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021278
 protein coding gene Chr13:105728808-105736950 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018848
 protein coding gene Chr13:94508687-94509233 (-)
CAST/EiJ MGP_CASTEiJ_G0020152
 protein coding gene Chr13:100879503-100893958 (-)
CBA/J MGP_CBAJ_G0020595
 protein coding gene Chr13:109904047-109915946 (-)
DBA/2J MGP_DBA2J_G0020719
 protein coding gene Chr13:98456411-98464679 (-)
FVB/NJ MGP_FVBNJ_G0020701
 protein coding gene Chr13:97201759-97206860 (-)
LP/J MGP_LPJ_G0020793
 protein coding gene Chr13:102699904-102709702 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020729
 protein coding gene Chr13:110141027-110156663 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021317
 protein coding gene Chr13:101163762-101172067 (-)
PWK/PhJ MGP_PWKPhJ_G0019905
 protein coding gene Chr13:97185053-97195374 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019727
 protein coding gene Chr13:97392480-97401065 (-)
WSB/EiJ MGP_WSBEiJ_G0020210
 protein coding gene Chr13:101631356-101639469 (-)



Homology
more
  • Human Ortholog
    KGD4, alpha-ketoglutarate dehydrogenase subunit 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KGD4, alpha-ketoglutarate dehydrogenase subunit 4
  • Synonyms
    DC47, MRPS36, MRP-S36
  • Links
    NCBI Gene ID: 92259
    neXtProt AC: NX_P82909
    UniProt: P82909

  • Chr Location
    5q13.2; chr5:69217760-69230158 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    13
  • cDNA Data
    10
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000061474 Ensembl Gene Model | MGI Sequence Detail 8705 C57BL/6J ±  kb
    transcript ENSMUST00000109333 Ensembl | MGI Sequence Detail 701 Not Applicable  
    polypeptide ENSMUSP00000104957 Ensembl | MGI Sequence Detail 102 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000010642 alpha-ketoglutarate dehydrogenase component 4
      (term hierarchy)
    • InterPro Domains
      IPR020373 Alpha-ketoglutarate dehydrogenase component 4/YMR-31
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 26
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:343143 Hevler JF, et al., MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex. Open Biol. 2023 Mar;13(3):220363
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory