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Mycbp Gene Detail
Summary
  • Symbol
    Mycbp
  • Name
    MYC binding protein
  • Synonyms
    5730488M09Rik, Amy-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891750
    NCBI Gene: 56309
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:123798806-123806043 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 57.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891750
 protein coding gene Chr4:123798625-123806062 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028745
 protein coding gene Chr4:125390666-125396997 (+)
A/J MGP_AJ_G0028705
 protein coding gene Chr4:120471647-120477963 (+)
AKR/J MGP_AKRJ_G0028658
 protein coding gene Chr4:123776322-123782650 (+)
BALB/cJ MGP_BALBcJ_G0028727
 protein coding gene Chr4:121070735-121079302 (+)
C3H/HeJ MGP_C3HHeJ_G0028442
 protein coding gene Chr4:123875826-123882180 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029169
 protein coding gene Chr4:130226508-130232835 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026442
 protein coding gene Chr4:113674427-113681757 (+)
CAST/EiJ MGP_CASTEiJ_G0027874
 protein coding gene Chr4:121886896-121894374 (+)
CBA/J MGP_CBAJ_G0028407
 protein coding gene Chr4:133522949-133529303 (+)
DBA/2J MGP_DBA2J_G0028556
 protein coding gene Chr4:120976177-120982530 (+)
FVB/NJ MGP_FVBNJ_G0028523
 protein coding gene Chr4:119589916-119596245 (+)
LP/J MGP_LPJ_G0028658
 protein coding gene Chr4:125687466-125693804 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028549
 protein coding gene Chr4:138488798-138498128 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029207
 protein coding gene Chr4:124135755-124142077 (+)
PWK/PhJ MGP_PWKPhJ_G0027595
 protein coding gene Chr4:117365332-117372916 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027422
 protein coding gene Chr4:119897787-119905383 (+)
WSB/EiJ MGP_WSBEiJ_G0027954
 protein coding gene Chr4:124206222-124215570 (+)



Homology
more
  • Human Ortholog
    MYCBP, MYC binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYCBP, MYC binding protein
  • Synonyms
    AMY-1
  • Links
    NCBI Gene ID: 26292
    neXtProt AC: NX_Q99417
    UniProt: Q99417

  • Chr Location
    1p34.3; chr1:38862490-38873378 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    2
  • Gene trapped
    7
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Mycbp
  • Find Mice (IMSR)
    10 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56309 NCBI Gene Model | MGI Sequence Detail 7238 C57BL/6J ±  kb
transcript NM_019660 RefSeq | MGI Sequence Detail 1485 C57BL/6  
polypeptide Q9EQS3 UniProt | EBI | MGI Sequence Detail 103 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 7
Other
Accession IDs
less
MGI:1915499, MGI:2140596, MGI:2140609
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:217391 Lin C, et al., Regulation of Sufu activity by p66beta and Mycbp provides new insight into vertebrate Hedgehog signaling. Genes Dev. 2014 Nov 15;28(22):2547-63
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory