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Arpp19 Gene Detail
Summary
  • Symbol
    Arpp19
  • Name
    cAMP-regulated phosphoprotein 19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891691
    NCBI Gene: 59046
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr9:74944896-74967595 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 42.25 cM, cytoband E1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891691
 protein coding gene Chr9:74944896-74967595 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035033
 protein coding gene Chr9:75315615-75341140 (+)
A/J MGP_AJ_G0035014
 protein coding gene Chr9:72685644-72708367 (+)
AKR/J MGP_AKRJ_G0034943
 protein coding gene Chr9:74429762-74452479 (+)
BALB/cJ MGP_BALBcJ_G0035006
 protein coding gene Chr9:72371252-72396285 (+)
C3H/HeJ MGP_C3HHeJ_G0034715
 protein coding gene Chr9:74901349-74923889 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035525
 protein coding gene Chr9:77326672-77349753 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032436
 protein coding gene Chr9:72058776-72081361 (+)
CAST/EiJ MGP_CASTEiJ_G0034037
 protein coding gene Chr9:75234472-75258608 (+)
CBA/J MGP_CBAJ_G0034688
 protein coding gene Chr9:79975434-80000813 (+)
DBA/2J MGP_DBA2J_G0034847
 protein coding gene Chr9:72361150-72383949 (+)
FVB/NJ MGP_FVBNJ_G0034789
 protein coding gene Chr9:71673738-71697040 (+)
LP/J MGP_LPJ_G0034928
 protein coding gene Chr9:75572274-75596781 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034830
 protein coding gene Chr9:81080191-81104483 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035547
 protein coding gene Chr9:74593945-74617402 (+)
PWK/PhJ MGP_PWKPhJ_G0033741
 protein coding gene Chr9:72645582-72668562 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033574
 protein coding gene Chr9:74812066-74834266 (+)
WSB/EiJ MGP_WSBEiJ_G0034149
 protein coding gene Chr9:74502974-74527737 (+)



Homology
more
  • Human Ortholog
    ARPP19, cAMP regulated phosphoprotein 19
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARPP19, cAMP regulated phosphoprotein 19
  • Synonyms
    ARPP16, ARPP-16, ARPP-19, ENSAL
  • Links
    NCBI Gene ID: 10776
    neXtProt AC: NX_P56211
    UniProt: P56211

  • Chr Location
    15q21.2; chr15:52547045-52569883 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit failure of gastrulation and prenatal lethality.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    1
  • cDNA Data
    10
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 59046 NCBI Gene Model | MGI Sequence Detail 22700 C57BL/6J ±  kb
    transcript NM_021548 RefSeq | MGI Sequence Detail 4032 C57BL/6  
    polypeptide P56212 UniProt | EBI | MGI Sequence Detail 112 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:2143339
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 13
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:294106 Soulez M, et al., Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models. Mol Cell Biol. 2019 Mar 15;39(6)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory