Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Relatm1Yuo
Name:	v-rel reticuloendotheliosis viral oncogene homolog A (avian); targeted mutation 1, Yuichi Obata
MGI ID:	MGI:1860444
Synonyms:	p65-, relA -
Gene:	Rela  Location: Chr19:5687511-5698158 bp, + strand  Genetic Position: Chr19, 4.34 cM, cytoband B1-3
Alliance:	Relatm1Yuo page

Germline Transmission:	Earliest citation of germline transmission: J:63099
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin selection cassette was inserted 3 base pairs downstream of the translation initiation codon. Northern analysis of total RNA isolated from homozygous mutant embryos showed an absence of transcript. (J:63099) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	67 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Rela Mutation:	24 strains or lines available

Original:	J:63099 Doi TS, et al., NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses. J Exp Med. 1997 Mar 3;185(5):953-61
All:	11 reference(s)