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Zftraf1 Gene Detail
Summary
  • Symbol
    Zftraf1
  • Name
    zinc finger TRAF type containing 1
  • Synonyms
    1110031M01Rik, Chrp, Cyhr1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859320
    NCBI Gene: 54151
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76531127-76541120 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 36.20 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859320
 protein coding gene Chr15:76527586-76541120 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022003
 protein coding gene Chr15:76735271-76753587 (-)
A/J MGP_AJ_G0021961
 protein coding gene Chr15:73930809-73947524 (-)
AKR/J MGP_AKRJ_G0021944
 protein coding gene Chr15:75937561-75954270 (-)
BALB/cJ MGP_BALBcJ_G0021970
 protein coding gene Chr15:73956121-73973138 (-)
C3H/HeJ MGP_C3HHeJ_G0021742
 protein coding gene Chr15:75982692-75999407 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022410
 protein coding gene Chr15:79597713-79618142 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019939
 protein coding gene Chr15:70587098-70603766 (-)
CAST/EiJ MGP_CASTEiJ_G0021261
 protein coding gene Chr15:76787148-76803899 (-)
CBA/J MGP_CBAJ_G0021709
 protein coding gene Chr15:82125587-82142410 (-)
DBA/2J MGP_DBA2J_G0021834
 protein coding gene Chr15:73467977-73484699 (-)
FVB/NJ MGP_FVBNJ_G0021814
 protein coding gene Chr15:72525450-72542668 (-)
LP/J MGP_LPJ_G0021905
 protein coding gene Chr15:76825299-76842043 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021839
 protein coding gene Chr15:87456304-87473868 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022430
 protein coding gene Chr15:76212395-76229156 (-)
PWK/PhJ MGP_PWKPhJ_G0021002
 protein coding gene Chr15:73631898-73649385 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020842
 protein coding gene Chr15:75905948-75922767 (-)
WSB/EiJ MGP_WSBEiJ_G0021313
 protein coding gene Chr15:76299415-76316130 (-)



Homology
more
  • Human Ortholog
    ZFTRAF1, zinc finger TRAF-type containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZFTRAF1, zinc finger TRAF-type containing 1
  • Synonyms
    CHRP, CYHR1
  • Links
    NCBI Gene ID: 50626
    neXtProt AC: NX_P0DTL6
    UniProt: P0DTL6

  • Chr Location
    8q24.3; chr8:144449582-144462871 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053929 Ensembl Gene Model | MGI Sequence Detail 9994 C57BL/6J ±  kb
transcript ENSMUST00000176274 Ensembl | MGI Sequence Detail 1854 Not Applicable  
polypeptide ENSMUSP00000134739 Ensembl | MGI Sequence Detail 412 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 11
Other
Accession IDs
less
MGI:2146152, MGI:2447817
References
more
  • Summaries
    All 52
    Diseases 1
    Gene Ontology 4
    Phenotypes 27
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory