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Epotm1Jae
Targeted Allele Detail
Summary
Symbol: Epotm1Jae
Name: erythropoietin; targeted mutation 1, Rudolf Jaenisch
MGI ID: MGI:1858038
Synonyms: Epo-
Gene: Epo  Location: Chr5:137481282-137484078 bp, - strand  Genetic Position: Chr5, 76.5 cM, cytoband G
Alliance: Epotm1Jae page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29254
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced a genomic fragment containing exons 2-5, which contain most of the coding region. (J:29254)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Epo Mutation:  31 strains or lines available
References
Original:  J:29254 Wu H, et al., Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell. 1995 Oct 6;83(1):59-67
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory