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Pms1tm1Lisk
Targeted Allele Detail
Summary
Symbol: Pms1tm1Lisk
Name: PMS1 homolog 1, mismatch repair system component; targeted mutation 1, Michael Liskay
MGI ID: MGI:1857948
Gene: Pms1  Location: Chr1:53228346-53336177 bp, - strand  Genetic Position: Chr1, 26.99 cM
Alliance: Pms1tm1Lisk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46382
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    An HPRT based cassette was used to replace an exon encoding amino acids 106-141. (J:46382)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Pms1tm1Lisk
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pms1 Mutation:  59 strains or lines available
References
Original:  J:46382 Prolla TA, et al., Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair. Nat Genet. 1998 Mar;18(3):276-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory