Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxc2tm1Blh
Name:	forkhead box C2; targeted mutation 1, Brigid L Hogan
MGI ID:	MGI:1857865
Synonyms:	Foxc2-, mfh1tm1
Gene:	Foxc2  Location: Chr8:121842910-121845634 bp, + strand  Genetic Position: Chr8, 70.33 cM
Alliance:	Foxc2tm1Blh page

Germline Transmission:	Earliest citation of germline transmission: J:39636
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A PGK-neomyin selection cassette replaced all of the coding sequences of the gene. In situ hybridization experiments on sections of homozygous embryos confirmed that no detectable transcript was expressed from this allele. (J:39636)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	148 assay results
In Structures Affected by this Mutation:	30 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxc2 Mutation:	15 strains or lines available

Original:	J:39636 Winnier GE, et al., The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. Genes Dev. 1997 Apr 1;11(7):926-40
All:	16 reference(s)