Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pax7tm1Pgr
Name:	paired box 7; targeted mutation 1, Peter Gruss
MGI ID:	MGI:1857831
Gene:	Pax7  Location: Chr4:139464373-139560839 bp, - strand  Genetic Position: Chr4, 70.83 cM
Alliance:	Pax7tm1Pgr page

Germline Transmission:	Earliest citation of germline transmission: J:32018
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin cassette was inserted into the first exon of the paired box. This targeting strategy was expected to abolish the DNA binding activity of the paired domain. (J:32018)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax7 Mutation:	39 strains or lines available

Original:	J:32018 Mansouri A, et al., Dysgenesis of cephalic neural crest derivatives in Pax7-/- mutant mice. Development. 1996 Mar;122(3):831-8
All:	17 reference(s)