Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prrx1tm1Tex
Name:	paired related homeobox 1; targeted mutation 1, University of Texas
MGI ID:	MGI:1857640
Synonyms:	Prx1-, Prx1LacZ, Prx-1neo
Gene:	Prrx1  Location: Chr1:163072688-163141279 bp, - strand  Genetic Position: Chr1, 70.53 cM
Alliance:	Prrx1tm1Tex page

Germline Transmission:	Earliest citation of germline transmission: J:25649
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A PGK-neomycin cassette was inserted into the 5' region of the homeobox domain. RT-PCR analysis failed to detect gene specific transcript in homozygous mutant animals. (J:25649)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	61 assay results
In Structures Affected by this Mutation:	39 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prrx1 Mutation:	31 strains or lines available

Original:	J:25649 Martin JF, et al., The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. Genes Dev. 1995 May 15;9(10):1237-49
All:	9 reference(s)