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Hoxa2tm1Grid
Targeted Allele Detail
Summary
Symbol: Hoxa2tm1Grid
Name: homeobox A2; targeted mutation 1, Tom Gridley
MGI ID: MGI:1857530
Synonyms: Hox1.11, Hoxa-2-, Hoxa2delta1
Gene: Hoxa2  Location: Chr6:52139397-52141811 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance: Hoxa2tm1Grid page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:16389
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of 159 bp of exon 1, intron 1 and the first 33 bp of exon 2 with a neomycin resistance cassette. (J:16389)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 123 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 26 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa2 Mutation:  21 strains or lines available
References
Original:  J:16389 Gendron-Maguire M, et al., Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell. 1993 Dec 31;75(7):1317-31
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory