Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Plaurtm1Jld
Name:	plasminogen activator, urokinase receptor; targeted mutation 1, Jay L Degen
MGI ID:	MGI:1857290
Synonyms:	Plaurtm1, uPAR-
Gene:	Plaur  Location: Chr7:24161909-24175393 bp, + strand  Genetic Position: Chr7, 10.92 cM, cytoband A3
Alliance:	Plaurtm1Jld page

Germline Transmission:	Earliest citation of germline transmission: J:26874
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3, encoding the second half of the amino-terminal uPA binding domain, was replaced by an HPRT minigene. (J:26874) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Plaur Mutation:	18 strains or lines available

Original:	J:26874 Bugge TH, et al., The receptor for urokinase-type plasminogen activator is not essential for mouse development or fertility. J Biol Chem. 1995 Jul 14;270(28):16886-94
All:	44 reference(s)