Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fyntm1Sor
Name:	Fyn proto-oncogene; targeted mutation 1, Philippe Soriano
MGI ID:	MGI:1857172
Synonyms:	fyn-
Gene:	Fyn  Location: Chr10:39245735-39441377 bp, + strand  Genetic Position: Chr10, 20.51 cM
Alliance:	Fyntm1Sor page

Germline Transmission:	Earliest citation of germline transmission: J:2242
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Replacement of a 3kb fragment containing the first coding exon of the gene with a neomycin cassette. (J:2242, J:97095)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Fyn Mutation:	37 strains or lines available

Original:	J:2242 Stein PL, et al., pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell. 1992 Sep 4;70(5):741-50
All:	168 reference(s)