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Amhtm1Bhr
Targeted Allele Detail
Summary
Symbol: Amhtm1Bhr
Name: anti-Mullerian hormone; targeted mutation 1, Richard R Behringer
MGI ID: MGI:1857126
Synonyms: AMH(-), AMHKO, delta1 (null), MIS-KO
Gene: Amh  Location: Chr10:80641077-80643482 bp, + strand  Genetic Position: Chr10, 39.72 cM
Alliance: Amhtm1Bhr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:21396
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 0.6 kb genomic fragment containing part of exon 1 and exon 2 was replaced with a neomycin selection cassette. (J:21396)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 41 assay results
3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Amh Mutation:  24 strains or lines available
References
Original:  J:21396 Behringer RR, et al., Mullerian-inhibiting substance function during mammalian sexual development. Cell. 1994 Nov 4;79(3):415-25
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory