Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Tgfatm1Ard
Name:	transforming growth factor alpha; targeted mutation 1, Ashley R Dunn
MGI ID:	MGI:1856577
Synonyms:	Tgfalpha -
Gene:	Tgfa  Location: Chr6:86172205-86252701 bp, + strand  Genetic Position: Chr6, 37.62 cM
Alliance:	Tgfatm1Ard page

Germline Transmission:	Earliest citation of germline transmission: J:4606
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin cassette was inserted into exon 3 of the gene. (J:4606)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Tgfa Mutation:	17 strains or lines available

Original:	J:4606 Mann GB, et al., Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell. 1993 Apr 23;73(2):249-61
All:	17 reference(s)