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Golga5 Gene Detail
Summary
  • Symbol
    Golga5
  • Name
    golgin A5
  • Synonyms
    Ret-II
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351475
    NCBI Gene: 27277
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:102435394-102464166 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 51.51 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    232 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351475
 protein coding gene Chr12:102435372-102464274 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020032
 protein coding gene Chr12:104096988-104125882 (+)
A/J MGP_AJ_G0019988
 protein coding gene Chr12:100103337-100133175 (+)
AKR/J MGP_AKRJ_G0019964
 protein coding gene Chr12:102943484-102972096 (+)
BALB/cJ MGP_BALBcJ_G0019974
 protein coding gene Chr12:100433229-100462610 (+)
C3H/HeJ MGP_C3HHeJ_G0019776
 protein coding gene Chr12:103405610-103436795 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020423
 protein coding gene Chr12:107353122-107381796 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018036
 protein coding gene Chr12:97123558-97152552 (+)
CAST/EiJ MGP_CASTEiJ_G0019322
 protein coding gene Chr12:98237146-98267157 (+)
CBA/J MGP_CBAJ_G0019748
 protein coding gene Chr12:111323206-111352812 (+)
DBA/2J MGP_DBA2J_G0019859
 protein coding gene Chr12:99622024-99650876 (+)
FVB/NJ MGP_FVBNJ_G0019848
 protein coding gene Chr12:98350649-98379246 (+)
LP/J MGP_LPJ_G0019935
 protein coding gene Chr12:103951998-103976865 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019888
 protein coding gene Chr12:114802648-114832855 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020452
 protein coding gene Chr12:102445920-102474622 (+)
PWK/PhJ MGP_PWKPhJ_G0019085
 protein coding gene Chr12:94178630-94209419 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018881
 protein coding gene Chr12:96629354-96659135 (+)
WSB/EiJ MGP_WSBEiJ_G0019376
 protein coding gene Chr12:103338947-103368327 (+)



Homology
more
  • Human Ortholog
    GOLGA5, golgin A5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GOLGA5, golgin A5
  • Synonyms
    GOLIM5, ret-II, RFG5
  • Links
    NCBI Gene ID: 9950
    neXtProt AC: NX_Q8TBA6
    UniProt: Q8TBA6

  • Chr Location
    14q32.12; chr14:92794305-92839947 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 4 alleles in 4 genetic backgrounds
    7 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout does not result in an obvious phenotype and does not affect Golgi apparatus morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    747
  • Tissues
    26
  • cDNA Data
    57
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021192 Ensembl Gene Model | MGI Sequence Detail 28773 C57BL/6J ±  kb
    transcript ENSMUST00000179218 Ensembl | MGI Sequence Detail 2827 Not Applicable  
    polypeptide ENSMUSP00000137305 Ensembl | MGI Sequence Detail 729 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 58
      cDNA 57
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 11
    • Earliest
      J:52425 Bascom RA, et al., Identification and characterization of golgin-84, a novel Golgi integral membrane protein a cyto-plasmic coiled-coil domain [published erratum appears in J Biol Chem 1999 Apr 30;274(18):12950]. J Biol Chem. 1999 Jan 29;274(5):2953-62
    • Latest
      J:242905 McGee LJ, et al., Golga5 is dispensable for mouse embryonic development and postnatal survival. Genesis. 2017 Jul;55(7)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory