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Slc25a14 Gene Detail
Summary
  • Symbol
    Slc25a14
  • Name
    solute carrier family 25 (mitochondrial carrier, brain), member 14
  • Synonyms
    BMCP1, UCP5, UCP5L, UCP5S
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330823
    NCBI Gene: 20523
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:47712333-47751171 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 25.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    225 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330823
protein coding gene ChrX:47712290-47751171 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035696
protein coding gene ChrX:43794497-43847577 (+)
A/J MGP_AJ_G0035679
protein coding gene ChrX:43656119-43695010 (+)
AKR/J MGP_AKRJ_G0035599
protein coding gene ChrX:44865699-44904672 (+)
BALB/cJ MGP_BALBcJ_G0035665
protein coding gene ChrX:43293455-43333594 (+)
C3H/HeJ MGP_C3HHeJ_G0035369
protein coding gene ChrX:44082462-44121075 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036194
protein coding gene ChrX:44817754-44861603 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033046
protein coding gene ChrX:41328206-41368204 (+)
CAST/EiJ MGP_CASTEiJ_G0034660
protein coding gene ChrX:31660502-31701859 (+)
CBA/J MGP_CBAJ_G0035343
protein coding gene ChrX:46082939-46130310 (+)
DBA/2J MGP_DBA2J_G0035497
protein coding gene ChrX:43485713-43525229 (+)
FVB/NJ MGP_FVBNJ_G0035446
protein coding gene ChrX:43203512-43241933 (+)
LP/J MGP_LPJ_G0035585
protein coding gene ChrX:44149884-44205496 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035484
protein coding gene ChrX:47511765-47552318 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036212
protein coding gene ChrX:43688478-43732683 (+)
PWK/PhJ MGP_PWKPhJ_G0034359
protein coding gene ChrX:31136046-31175473 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034204
protein coding gene ChrX:32469004-32514447 (+)
WSB/EiJ MGP_WSBEiJ_G0034804
protein coding gene ChrX:43327111-43367047 (+)



Homology
more
  • Human Ortholog
    SLC25A14, solute carrier family 25 member 14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A14, solute carrier family 25 member 14
  • Synonyms
    BMCP1, UCP5
  • Links
    NCBI Gene ID: 9016
    neXtProt AC: NX_O95258
    UniProt: O95258

  • Chr Location
    Xq26.1; chrX:130339888-130373361 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20523 NCBI Gene Model | MGI Sequence Detail 38839 C57BL/6J ±  kb
transcript NM_001403261 RefSeq | MGI Sequence Detail 1819 ZRU/MplStud  
polypeptide Q9Z2B2 UniProt | EBI | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 30
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1333769
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:51513 Sanchis D, et al., BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast. J Biol Chem. 1998 Dec 18;273(51):34611-5
  • Latest
    J:242707 Ji F, et al., UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex. Stem Cells. 2017 Jun;35(6):1479-1492

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory