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Umps Gene Detail
Summary
  • Symbol
    Umps
  • Name
    uridine monophosphate synthetase
  • Synonyms
    1700095D23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298388
    NCBI Gene: 22247
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:33775152-33787408 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 24.26 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1298388
 protein coding gene Chr16:33775152-33787408 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022760
 protein coding gene Chr16:32198688-32210944 (-)
A/J MGP_AJ_G0022725
 protein coding gene Chr16:30644003-30656259 (-)
AKR/J MGP_AKRJ_G0022698
 protein coding gene Chr16:31727117-31739373 (-)
BALB/cJ MGP_BALBcJ_G0022727
 protein coding gene Chr16:30761625-30773911 (-)
C3H/HeJ MGP_C3HHeJ_G0022492
 protein coding gene Chr16:31854894-31867156 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023176
 protein coding gene Chr16:32907306-32919560 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020694
 protein coding gene Chr16:30988037-31000712 (-)
CAST/EiJ MGP_CASTEiJ_G0022020
 protein coding gene Chr16:32039164-32051552 (-)
CBA/J MGP_CBAJ_G0022462
 protein coding gene Chr16:34245340-34257602 (-)
DBA/2J MGP_DBA2J_G0022595
 protein coding gene Chr16:30467265-30479531 (-)
FVB/NJ MGP_FVBNJ_G0022570
 protein coding gene Chr16:30459500-30472678 (-)
LP/J MGP_LPJ_G0022662
 protein coding gene Chr16:31920162-31932412 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022589
 protein coding gene Chr16:33588370-33600626 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023188
 protein coding gene Chr16:31739829-31752083 (-)
PWK/PhJ MGP_PWKPhJ_G0021761
 protein coding gene Chr16:30847157-30859725 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021590
 protein coding gene Chr16:31526949-31540806 (-)
WSB/EiJ MGP_WSBEiJ_G0022064
 protein coding gene Chr16:31698952-31711204 (-)



Homology
more
  • Human Ortholog
    UMPS, uridine monophosphate synthetase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UMPS, uridine monophosphate synthetase
  • Synonyms
    OPRT
  • Links
    NCBI Gene ID: 7372
    neXtProt AC: NX_P11172
    UniProt: P11172

  • Chr Location
    3q21.2; chr3:124730433-124749273 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human UMPS associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    812
  • Tissues
    102
  • cDNA Data
    19
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22247 NCBI Gene Model | MGI Sequence Detail 12257 C57BL/6J ±  kb
transcript NM_009471 RefSeq | MGI Sequence Detail 3484 C57BL/6  
polypeptide P13439 UniProt | EBI | MGI Sequence Detail 481 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    Genomic 1
    cDNA 19
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920822, MGI:2146334, MGI:2146531, MGI:2146687
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 8
  • Earliest
    J:307213 Kavipurapu PR, et al., Purification, size, and properties of the complex of orotate phosphoribosyltransferase: orotidylate decarboxylase from mouse Ehrlich ascites carcinoma. J Biol Chem. 1976 Sep 25;251(18):5589-99
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory