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Slc52a2 Gene Detail
Summary
  • Symbol
    Slc52a2
  • Name
    solute carrier protein 52, member 2
  • Synonyms
    2010003P03Rik, D15Ertd747e, GPCR42, Gpr172b, PAR2, Rfvt2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289288
    NCBI Gene: 52710
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76423032-76428808 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 36.04 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    17 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289288
 protein coding gene Chr15:76422994-76432078 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021998
 protein coding gene Chr15:76618101-76621288 (+)
A/J MGP_AJ_G0021956
 protein coding gene Chr15:73828299-73831486 (+)
AKR/J MGP_AKRJ_G0021939
 protein coding gene Chr15:75829111-75832298 (+)
BALB/cJ MGP_BALBcJ_G0021965
 protein coding gene Chr15:73857548-73860735 (+)
C3H/HeJ MGP_C3HHeJ_G0021737
 protein coding gene Chr15:75876973-75880160 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022405
 protein coding gene Chr15:79485624-79488811 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019934
 protein coding gene Chr15:70491877-70494145 (+)
CAST/EiJ MGP_CASTEiJ_G0021256
 protein coding gene Chr15:76679135-76683440 (+)
CBA/J MGP_CBAJ_G0021704
 protein coding gene Chr15:81999293-82002480 (+)
DBA/2J MGP_DBA2J_G0021829
 protein coding gene Chr15:73365761-73368948 (+)
FVB/NJ MGP_FVBNJ_G0021809
 protein coding gene Chr15:72422574-72425761 (+)
LP/J MGP_LPJ_G0021900
 protein coding gene Chr15:76717716-76720903 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021834
 protein coding gene Chr15:87328531-87331719 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022425
 protein coding gene Chr15:76083461-76091273 (+)
PWK/PhJ MGP_PWKPhJ_G0020997
 protein coding gene Chr15:73531426-73534612 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020837
 protein coding gene Chr15:75801984-75805131 (+)
WSB/EiJ MGP_WSBEiJ_G0021308
 protein coding gene Chr15:76190430-76193613 (+)



Homology
more
  • Human Ortholog
    SLC52A1, solute carrier family 52 member 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC52A1, solute carrier family 52 member 1
  • Synonyms
    GPCR42, GPR172B, hRFT1, huPAR-2, PAR2, RBFVD, RFT1, RFVT1
  • Links
    NCBI Gene ID: 55065
    neXtProt AC: NX_Q9NWF4
    UniProt: Q9NWF4

  • Chr Location
    17p13.2; chr17:5032600-5052009 (-)  GRCh38
  • Human Ortholog
    SLC52A2, solute carrier family 52 member 2
  • Synonyms
    BVVLS2, D15Ertd747e, GPCR41, GPR172A, hRFT3, HuPAR-1, PAR1, RFT3, RFVT2
  • Links
    NCBI Gene ID: 79581
    neXtProt AC: NX_Q9HAB3
    UniProt: Q9HAB3

  • Chr Location
    8q24.3; chr8:144333957-144361286 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human SLC52A1,SLC52A2 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    36 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele die prior to E10.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    67
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022560 Ensembl Gene Model | MGI Sequence Detail 5777 C57BL/6J ±  kb
    transcript ENSMUST00000023220 Ensembl | MGI Sequence Detail 5289 Not Applicable  
    polypeptide ENSMUSP00000023220 Ensembl | MGI Sequence Detail 450 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000008188 solute carrier family 52, riboflavin transporter, member 1
      (term hierarchy)
    • InterPro Domains
      IPR009357 Solute carrier family 52, riboflavin transporter
    Molecular
    Reagents
    less
    • All nucleic 69
      cDNA 67
      Primer pair 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1923771
    References
    more
    • Summaries
      All 68
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 6
      Phenotypes 36
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:311893 Jin C, et al., Complete Deletion of Slc52a2 Causes Embryonic Lethality in Mice. Biol Pharm Bull. 2021;44(2):283-286
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory