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Shd Gene Detail
Summary
  • Symbol
    Shd
  • Name
    src homology 2 domain-containing transforming protein D
  • Feature Type
    protein coding gene
  • IDs
    MGI:1099461
    NCBI Gene: 20420
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:56277467-56283625 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 29.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1099461
 protein coding gene Chr17:56276828-56283625 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023904
 protein coding gene Chr17:57593019-57599181 (+)
A/J MGP_AJ_G0023864
 protein coding gene Chr17:56041648-56047798 (+)
AKR/J MGP_AKRJ_G0023833
 protein coding gene Chr17:56721753-56727903 (+)
BALB/cJ MGP_BALBcJ_G0023865
 protein coding gene Chr17:55875923-55882084 (+)
C3H/HeJ MGP_C3HHeJ_G0023628
 protein coding gene Chr17:57432615-57438777 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024309
 protein coding gene Chr17:59876179-59882329 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021756
 protein coding gene Chr17:52560205-52566429 (+)
CAST/EiJ MGP_CASTEiJ_G0023111
 protein coding gene Chr17:57739743-57746082 (+)
CBA/J MGP_CBAJ_G0023605
 protein coding gene Chr17:62168575-62174737 (+)
DBA/2J MGP_DBA2J_G0023733
 protein coding gene Chr17:54776080-54782242 (+)
FVB/NJ MGP_FVBNJ_G0023699
 protein coding gene Chr17:54292556-54298718 (+)
LP/J MGP_LPJ_G0023813
 protein coding gene Chr17:58315546-58321708 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023726
 protein coding gene Chr17:61740057-61746219 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024354
 protein coding gene Chr17:57102378-57108539 (+)
PWK/PhJ MGP_PWKPhJ_G0022856
 protein coding gene Chr17:54117732-54124239 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022668
 protein coding gene Chr17:53861849-53868015 (+)
WSB/EiJ MGP_WSBEiJ_G0023175
 protein coding gene Chr17:57712145-57718301 (+)



Homology
more
  • Human Ortholog
    SHD, Src homology 2 domain containing transforming protein D
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SHD, Src homology 2 domain containing transforming protein D
  • Links
    NCBI Gene ID: 56961
    neXtProt AC: NX_Q96IW2
    UniProt: Q96IW2

  • Chr Location
    19p13.3; chr19:4279069-4290722 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    17
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039154 Ensembl Gene Model | MGI Sequence Detail 6159 C57BL/6J ±  kb
transcript ENSMUST00000223629 Ensembl | MGI Sequence Detail 1430 Not Applicable  
polypeptide ENSMUSP00000153605 Ensembl | MGI Sequence Detail 344 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    Genomic 2
    cDNA 17

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146835
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:43082 Oda T, et al., Identification and characterization of two novel SH2 domain-containing proteins from a yeast two hybrid screen with the ABL tyrosine kinase. Oncogene. 1997 Sep;15(11):1255-62
  • Latest
    J:317822 Chern T, et al., Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory